Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614227 | 0.80 | NOX1 (0.43) | LMNAHTTSMN1; SMN2ALDH1A1ALOX12 | |
| SCHEMBL1257788 | 0.79 | SRC (0.62) | RAB9ANPC1MEN1KMT2ASRC | |
| SCHEMBL11279235 | 0.79 | PYCR1 (0.40) | RAB9ANPC1TP53TDP1MEN1 | |
| SCHEMBL3031232 | 0.78 | TP53 (0.44) | RAB9ANPC1TP53TDP1MEN1 | |
| Hydrochloric Acid SCHEMBL2530248 | 0.78 | SRC (0.61) | RAB9ANPC1MEN1KMT2ASRC | |
| SCHEMBL18780401 | 0.78 | TAAR1 (0.42) | RAB9ANPC1TP53TDP1MEN1 | |
| SCHEMBL14729157 | 0.77 | NPC1 (0.46) | RAB9ANPC1TP53TDP1MEN1 | |
| SCHEMBL10456035 | 0.75 | TP53 (0.41) | RAB9ANPC1TP53TDP1MEN1 | |
| SCHEMBL1257786 | 0.75 | NPSR1 (0.45) | RAB9ANPC1TP53TDP1MEN1 | |
| SCHEMBL17562017 | 0.75 | TP53 (0.41) | RAB9ANPC1TP53TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405873-A | Antilipemic, anticholesterol agents; treating arterio-sclerosis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0587430-A1 | Substituted acetamide derivatives for treatment of hypocholesterolaemia, hyperlipaemia and arteriosclerosis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-03-16 | — | — | EP | disclosed |