Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 5/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17564316 | 0.95 | KDM4E (0.39) | APEX1KDM4EKMT2ASYKZAP70 | |
| SCHEMBL17563731 | 0.81 | KDM4E (0.50) | KDM4EKMT2ASYKZAP70ALDH1A1 | |
| SCHEMBL17563722 | 0.80 | KDM4E (0.40) | APEX1KDM4EKMT2ASYKZAP70 | |
| SCHEMBL18757520 | 0.79 | KDM4E (0.51) | KDM4EKMT2ASYKZAP70ALDH1A1 | |
| SCHEMBL18757519 | 0.78 | KDM4E (0.42) | APEX1KDM4EKMT2AALDH1A1CSNK2A2 | |
| SCHEMBL18466736 | 0.78 | KDM4E (0.46) | APEX1KDM4EKMT2ASYKALDH1A1 | |
| SCHEMBL17577112 | 0.77 | KDM4E (0.38) | APEX1KDM4EKMT2ASYKZAP70 | |
| SCHEMBL17564309 | 0.77 | KDM4E (0.38) | APEX1KDM4EKMT2ASYKZAP70 | |
| SCHEMBL18466735 | 0.77 | KDM4E (0.38) | APEX1KDM4EKMT2ASYKZAP70 | |
| SCHEMBL17563729 | 0.77 | CXCR4 (0.36) | SYKZAP70SMN1; SMN2CXCR4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016036847-A9 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2017-04-20 | — | — | WO | disclosed |
| WO-2016036847-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2016-03-10 | — | — | WO | disclosed |