Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 7/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 6/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.30 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18757583 | 0.83 | CXCR4 (0.38) | CXCR4SYKCYP1A2CYP2D6CDK1 | |
| SCHEMBL17563812 | 0.81 | CXCL12 (0.39) | CXCR4SYKCDK1PRKCAZAP70 | |
| SCHEMBL17576144 | 0.81 | HSP90AA1 (0.40) | CXCR4CYP1A2CDK1PRKCASMN1; SMN2 | |
| SCHEMBL17563879 | 0.80 | — | — | |
| SCHEMBL17563730 | 0.78 | CXCR4 (0.46) | CXCR4SYKCYP1A2CYP2D6ZAP70 | |
| SCHEMBL17563735 | 0.78 | LMNA (0.41) | CXCR4SYKCYP1A2CDK1ZAP70 | |
| SCHEMBL18757549 | 0.78 | CA1 (0.41) | CXCR4SYKCYP1A2CDK1ZAP70 | |
| SCHEMBL17563723 | 0.77 | APEX1 (0.40) | CXCR4SYKZAP70SMN1; SMN2KCNH2 | |
| SCHEMBL17563727 | 0.76 | MEN1 (0.47) | CYP1A2CYP2D6SMN1; SMN2HSP90AA1STK17A | |
| SCHEMBL17563813 | 0.75 | HSP90AA1 (0.51) | CXCR4SMN1; SMN2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016036847-A9 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2017-04-20 | — | — | WO | disclosed |
| WO-2016036847-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2016-03-10 | — | — | WO | disclosed |