Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 6/20 | 0.35 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.34 |
| ▸ | CDK1 | P06493 | 4/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | FES | P07332 | 1/20 | 0.32 |
| ▸ | ROS1 | P08922 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6256220 | 0.84 | CYP1A2 (0.35) | CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL17563729 | 0.83 | CXCR4 (0.36) | CXCR4SYKZAP70CDK1AURKB | |
| SCHEMBL11684387 | 0.81 | CYP1A2 (0.46) | FLT3CYP1A2CYP2D6 | |
| SCHEMBL17563730 | 0.81 | CXCR4 (0.46) | CXCR4SYKZAP70AURKBCYP1A2 | |
| SCHEMBL9292846 | 0.80 | TSHR (0.41) | CLK4CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL6448611 | 0.79 | — | — | |
| SCHEMBL7093264 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL11460652 | 0.78 | KCNH3 (0.43) | DYRK1ASMN1; SMN2HTR7 | |
| SCHEMBL17563735 | 0.77 | LMNA (0.41) | CXCR4SYKZAP70CDK1CYP1A2 | |
| SCHEMBL18757540 | 0.77 | CXCR4 (0.41) | CXCR4SYKZAP70CDK1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016036847-A9 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2017-04-20 | — | — | WO | disclosed |