SCHEMBL1756491

SCHEMBL1756491

C=C(C)C(=O)OCCO.C=C(CC=C(C)C(=O)O)C(=O)OC

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.37
TSHR P16473 4/20 0.36
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8318224 0.94 ALDH1A1 (0.42) ALDH1A1THRBTSHR
SCHEMBL4606541 0.93 TSHR (0.47) ALDH1A1THRBTSHRPOLBAPEX1
SCHEMBL15512400 0.90 THRB (0.40) ALDH1A1THRBTSHRPOLBAPEX1
SCHEMBL1179097 0.89 TSHR (0.46) ALDH1A1THRBTSHRPOLBAPEX1
Methacrylic Acid SCHEMBL4338888 0.88 TSHR (0.34) THRBTSHR
SCHEMBL1161024 0.88 TSHR (0.36) THRBTSHR
SCHEMBL8431539 0.87 ALDH1A1 (0.52) ALDH1A1THRBTSHR
SCHEMBL1813995 0.87 ALDH1A1 (0.52) ALDH1A1THRBTSHR
SCHEMBL7598695 0.87 TSHR (0.46) ALDH1A1THRBTSHRPOLBAPEX1
SCHEMBL3075214 0.86 TSHR (0.51) ALDH1A1THRBTSHRPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7943353-B2 Multi-layer cell encapsulation for tissue engineering AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-05-17 US disclosed
US-20090286278-A1 MULTI-LAYER CELL ENCAPSULATION FOR TISSUE ENGINEERING AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-11-19 US disclosed
US-20050220891-A1 Multi-layer cell encapsulation for tissue engineering AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2005-10-06 US disclosed
US-6916640-B2 Multi-layer cell encapsulation for tissue engineering AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2005-07-12 US disclosed
US-6641832-B2 For promoting extensive vascularization when implanted in animal tissue, therapy, wound healing SEFTON MICHAEL VIVIAN (CA) 2003-11-04 US disclosed
EP-1141266-A4 EXPRESSION VECTORS COMPRISING MULTIPLE SHEAR STRESS RESPONSIVE ELEMENTS (SSRE) AND A GENE OF INTEREST AND METHODS OF USE THEREOF FLORENCE MEDICAL LTD (IL) 2002-09-25 EP disclosed
US-6440726-B1 GENE THERAPY; CARDIOVASCULAR DISEASES; FOR STIMULATING THE FORMATION, MATURATION OR REGRESSION OF BLOOD VESSELS FLORENCE MEDICAL, LTD. (IL) 2002-08-27 US disclosed
US-20020094569-A1 Multi-layer cell encapsulation for tissue engineering AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2002-07-18 US disclosed
US-20020037308-A1 Angiogenic material and uses thereof SEFTON MICHAEL VIVIAN (CA) 2002-03-28 US disclosed
EP-1141266-A2 EXPRESSION VECTORS COMPRISING MULTIPLE SHEAR STRESS RESPONSIVE ELEMENTS (SSRE) AND A GENE OF INTEREST AND METHODS OF USE THEREOF Florence Medical Ltd. (IL) 2001-10-10 EP disclosed
US-6261585-B1 INCREASING BLOOD FLOW TO ISCHEMIC AANIMAL TISSUE SEFTON MICHAEL VIVIAN (CA) 2001-07-17 US disclosed
WO-2000039275-A2 MULTIPLE SHEAR STRESS RESPONSIVE ELEMENTS (SSRE) AND METHODS OF USE THEREOF FLORENCE MEDICAL LTD. (IL) 2000-07-06 WO disclosed
WO-1997016176-A1 ANGIOGENIC MATERIAL AND USES THEREOF SEFTON MICHAEL VIVIAN (CA) 1997-05-09 WO disclosed