Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CLPP | Q16740 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17565140 | 0.88 | ACACB (0.47) | ACACBKMT2ALMNASMN1; SMN2NOD1 | |
| SCHEMBL13499612 | 0.85 | KMT2A (0.65) | ACACBKMT2ALMNASMN1; SMN2NOD1 | |
| SCHEMBL2095548 | 0.84 | ACACB (0.57) | ACACBKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4157838 | 0.82 | MEN1 (0.58) | KDM4EALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL17919674 | 0.82 | SIGMAR1 (0.60) | KMT2ALMNASMN1; SMN2NOD1HTT | |
| SCHEMBL30023861 | 0.82 | SIGMAR1 (0.60) | KMT2ALMNASMN1; SMN2NOD1HTT | |
| SCHEMBL17565148 | 0.82 | ACACB (0.55) | ACACBKDM4EALDH1A1KMT2AABCB1 | |
| SCHEMBL4517559 | 0.79 | ACACB (0.66) | ACACBKDM4EKMT2ALMNASMN1; SMN2 | |
| SCHEMBL28419536 | 0.79 | ACACB (0.52) | ACACBKDM4EALDH1A1KMT2ALMNA | |
| Potassium Ion SCHEMBL4527368 | 0.78 | ACACB (0.57) | ACACBKDM4EALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687507-B1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-03-09 | — | — | EP | disclosed |