Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MOGAT2 | Q3SYC2 | 4/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095548 | 0.82 | ACACB (0.57) | ACACBKDM4EALDH1A1ABCB1KMT2A | |
| SCHEMBL17565147 | 0.82 | ACACB (0.57) | ACACBKDM4EALDH1A1ABCB1KMT2A | |
| SCHEMBL15435247 | 0.81 | MOGAT2 (0.69) | ACACBMOGAT2ABCB1KMT2A | |
| SCHEMBL17565144 | 0.78 | MOGAT2 (0.69) | MOGAT2 | |
| Potassium Ion SCHEMBL4527368 | 0.78 | ACACB (0.57) | ACACBKDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL15435308 | 0.77 | MOGAT2 (0.57) | MOGAT2KMT2A | |
| SCHEMBL4157838 | 0.77 | MEN1 (0.58) | KDM4EALDH1A1KMT2A | |
| SCHEMBL4517559 | 0.76 | ACACB (0.66) | ACACBKDM4EKMT2AHDAC6 | |
| SCHEMBL15435213 | 0.76 | MOGAT2 (0.81) | MOGAT2 | |
| SCHEMBL1263457 | 0.75 | HDAC6 (0.62) | ACACBKDM4EKMT2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687507-B1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-03-09 | — | — | EP | disclosed |