Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129200 | 0.88 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL1756535 | 0.85 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL5327956 | 0.85 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL28730048 | 0.80 | TAS1R3 (0.34) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL31643990 | 0.78 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL9945871 | 0.77 | TAS1R3 (0.35) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10489243 | 0.76 | TAS1R3 (0.32) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10585715 | 0.76 | — | — | |
| SCHEMBL12912877 | 0.74 | TAS1R3 (0.34) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL24250416 | 0.72 | TAS1R3 (0.33) | TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281439-B1 | ESTERS OF CYCLOPROPANECARBOXYLIC ACIDS RELATED TO PYRETHRIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PARASITICIDES | ROUSSEL-UCLAF (FR) | 1991-06-12 | — | — | EP | claimed |
| US-4939172-A | Novel cyclopropane carboxylates | ROUSSEL UCLAF (FR) | 1990-07-03 | — | — | US | disclosed |