Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28148504 | 0.84 | GRM5 (0.47) | GRM5CHRNB2CHRNA4CYP2D6CYP2C19 | |
| SCHEMBL5240290 | 0.81 | GRM5 (0.41) | GRM5TLR7CHRNB2CHRNA4HSP90AA1 | |
| SCHEMBL31036005 | 0.77 | CHRNB2 (0.40) | GRM5TLR7CHRNB2CHRNA4CYP2C19 | |
| SCHEMBL29263693 | 0.77 | CHRNB2 (0.40) | GRM5TLR7CHRNB2CHRNA4CYP2C19 | |
| SCHEMBL15870932 | 0.76 | GRM5 (0.59) | GRM5HSP90AA1KDM4E | |
| SCHEMBL31286309 | 0.76 | GRM5 (0.59) | GRM5HSP90AA1KDM4E | |
| SCHEMBL408472 | 0.73 | GRM5 (0.49) | GRM5TLR8 | |
| SCHEMBL15870983 | 0.73 | — | — | |
| SCHEMBL29994137 | 0.73 | — | — | |
| SCHEMBL5094393 | 0.72 | GRM5 (0.35) | GRM5TLR7CYP2D6CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975988-B2 | Epoxy resins comprising a pyrazine-containing compound | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-22 | — | — | US | disclosed |
| US-20160068627-A1 | EPOXY RESINS COMPRISING A PYRAZINE-CONTAINING COMPOUND | 3M INNOVATIVE PROPERTIES COMPANY | 2016-03-10 | — | — | US | disclosed |