Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 4/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17567286 | 0.84 | GRM5 (0.45) | GRM5HSP90AA1CYP2C19CYP2A6CYP2D6 | |
| SCHEMBL15870932 | 0.79 | GRM5 (0.59) | GRM5HSP90AA1POLBKDM4EHAO1 | |
| SCHEMBL31286309 | 0.79 | GRM5 (0.59) | GRM5HSP90AA1POLBKDM4EHAO1 | |
| SCHEMBL5240290 | 0.76 | GRM5 (0.41) | GRM5HSP90AA1POLBCHRNB2CHRNA4 | |
| SCHEMBL29994137 | 0.76 | — | — | |
| SCHEMBL15870983 | 0.76 | — | — | |
| SCHEMBL23583669 | 0.73 | GRM5 (0.42) | GRM5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4637898 | 0.72 | GRM5 (0.49) | GRM5HSP90AA1KDM4EHAO1 | |
| SCHEMBL31036005 | 0.72 | CHRNB2 (0.40) | GRM5CYP2C19CYP2C9POLBCHRNB2 | |
| SCHEMBL29263693 | 0.72 | CHRNB2 (0.40) | GRM5CYP2C19CYP2C9POLBCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106660994-A | Phosphatidylinositol 3-kinase inhibitors | 吉利德科学公司 | 2017-05-10 | — | — | CN | disclosed |