SCHEMBL175685

SCHEMBL175685

CSc1cc(N)c(C)c(N)c1SC

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ALDH1A1 P00352 3/20 0.33
TP53 P04637 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
CYP3A4 P08684 2/20 0.33
TSHR P16473 1/20 0.33
ALOX15 P16050 3/20 0.32
HSD17B10 Q99714 2/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ALOX12 P18054 1/20 0.31
KMT2A Q03164 1/20 0.31
THRB P10828 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8934247 0.82 NPC1 (0.31) NPC1RAB9A
SCHEMBL308607 0.82 NPC1 (0.31) NPC1RAB9A
SCHEMBL15299 0.82 NPC1 (0.31) NPC1RAB9A
SCHEMBL9130885 0.81
SCHEMBL7190301 0.77 NPC1 (0.31) NPC1RAB9A
SCHEMBL28463583 0.77 NPC1 (0.31) NPC1RAB9A
SCHEMBL175015 0.77 ALDH1A1 (0.39) ALDH1A1TP53TDP1CYP3A4TSHR
SCHEMBL16781734 0.76
SCHEMBL10572302 0.73 NPC1 (0.30) NPC1RAB9A
SCHEMBL15256900 0.71 ALDH1A1 (0.32) ALDH1A1TP53TDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2814860-A1 ELASTOMERS FOR PAPER MILL EQUIPMENT Dow Global Technologies LLC (US) 2014-12-24 EP claimed
US-8557947-B2 Compositions useful in golf balls THE HANSON GROUP, LLC (US) 2013-10-15 US claimed
WO-2013122812-A1 ELASTOMERS FOR PAPER MILL EQUIPMENT DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-22 WO claimed
US-8324336-B2 Compositions useful in golf balls THE HANSON GROUP, LLC (US) 2012-12-04 US claimed
US-20100144467-A1 COMPOSITIONS USEFUL IN GOLF BALLS THE HANSON GROUP, LLC (US) 2010-06-10 US claimed
US-20090105013-A1 ULTRAVIOLET LIGHT RESISTANT POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SLAGEL EDWIN CHARLES 2009-04-23 US claimed
WO-2008150865-A2 COMPOSITIONS USEFUL IN GOLF BALLS THE HANSON GROUP LLC (US) 2008-12-11 WO claimed
US-6964621-B2 Water resistant polyurea elastomers for golf equipment ACUSHNET COMPANY (US) 2005-11-15 US claimed
US-11912813-B2 Urethane resin using polyrotaxane, and pad for polishing TOKUYAMA CORPORATION (JP) 2024-02-27 US disclosed
US-20230390611-A1 GOLF BALL BRIDGESTONE SPORTS CO., LTD. (JP) 2023-12-07 US disclosed
WO-2023234394-A1 ASYMMETRIC DIAMINE-CONTAINING AGENT AND RESIN, AND USE THEREOF 住友化学株式会社 2023-12-07 WO disclosed
WO-2023062991-A1 METHOD FOR PRODUCING COATING FILM AND MULTILAYER COATING FILM 日本ペイント・インダストリアルコーティングス株式会社 2023-04-20 WO disclosed
US-20210155736-A1 URETHANE RESIN USING POLYROTAXANE, AND PAD FOR POLISHING TOKUYAMA CORPORATION (JP) 2021-05-27 US disclosed
EP-3778688-A1 URETHANE RESIN USING POLYROTAXANE, AND PAD FOR POLISHING Tokuyama Corporation (JP) 2021-02-17 EP disclosed
US-5013813-A Coatings for roofs and floors, reaction injection molding materials TEXACO CHEMICAL COMPANY (US) 1991-05-07 US disclosed
EP-0420420-A2 Sprayable and pourable polyurea elastomer TEXACO CHEMICAL COMPANY (US) 1991-04-03 EP disclosed
US-4948861-A N,N'-dialkylphenylenediamines as curing agents in polyurethane and polyurea manufacture by reaction injection molding UOP (US) 1990-08-14 US disclosed
US-4847347-A MOLDING MATERIALS UOP (US) 1989-07-11 US disclosed
US-4806616-A N-N'-dialkylphenylenediamines as curing agents in polyurethane and polyurea manufacture by reaction injection molding UOP INC. (US) 1989-02-21 US disclosed
US-4736009-A Partially alkylated triamines and higher polyamines as curing agents in polyurethane manufacture by reaction injection molding UOP INC. (US) 1988-04-05 US disclosed