⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572302 | 0.82 | NPC1 (0.30) | — | |
| SCHEMBL15299 | 0.81 | NPC1 (0.31) | — | |
| SCHEMBL175685 | 0.81 | NPC1 (0.35) | — | |
| SCHEMBL16781734 | 0.80 | — | — | |
| SCHEMBL28463583 | 0.76 | NPC1 (0.31) | — | |
| SCHEMBL8934247 | 0.76 | NPC1 (0.31) | — | |
| SCHEMBL175015 | 0.76 | ALDH1A1 (0.39) | — | |
| SCHEMBL9578834 | 0.74 | — | — | |
| SCHEMBL30035958 | 0.73 | NPC1 (0.36) | — | |
| SCHEMBL8764611 | 0.73 | NPC1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253593-B1 | PURIFICATION OF (HYDROCARBYLTHIO) AROMATIC AMINES | ETHYL CORPORATION (US) | 1990-06-06 | — | — | EP | claimed |
| US-4727191-A | WASHING WITH ACID | ETHYL CORPORATION (US) | 1988-02-23 | — | — | US | claimed |
| EP-0253593-A1 | Purification of (hydrocarbylthio) aromatic amines | ETHYL CORPORATION (US) | 1988-01-20 | — | — | EP | claimed |
| US-5382695-A | Method for DMTDA production | ALBEMARLE CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0193872-B1 | DI(ALKYLTHIO) DIAMINE CHAIN EXTENDERS FOR POLYURETHANE ELASTOMERS | ETHYL CORPORATION (US) | 1993-03-31 | — | — | EP | disclosed |
| EP-0228190-B1 | RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION | ETHYL CORPORATION (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0329821-A2 | Polyhydroxyalkane/aromatic diamine chain extenders | ETHYL CORPORATION (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4786656-A | FOR POLYURETHANES | ETHYL CORPORATION (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0289870-A2 | Epoxy resin compositions | ETHYL CORPORATION (US) | 1988-11-09 | — | — | EP | disclosed |
| US-4727191-A | WASHING WITH ACID | ETHYL CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0228190-A2 | RIM polyurethanes comprising mixed diamine chain extenders and process and composition for their production | ETHYL CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4631298-A | REACTION INJECTION MOLDING POLYURETHANES | ETHYL CORPORATION (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0193872-A2 | Di(alkylthio) diamine chain extenders for polyurethane elastomers | ETHYL CORPORATION (US) | 1986-09-10 | — | — | EP | disclosed |
| US-4595742-A | Formed by reacting polyisocyanate, an organic active hydrogen group containing compound, and a chain extender comprising an aromatic diamine | ETHYL CORPORATION (US) | 1986-06-17 | — | — | US | disclosed |