SCHEMBL175015

SCHEMBL175015

CSc1cc(C)c(N)c(N)c1SC

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364269 0.82 ALDH1A1 (0.39) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL48465 0.82 ALDH1A1 (0.39) ALDH1A1TP53CYP3A4TSHRTDP1
Ammonia Solution, Strong SCHEMBL9566348 0.80 ALDH1A1 (0.37) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL175685 0.77 NPC1 (0.35) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL9130885 0.76
SCHEMBL15256900 0.76 ALDH1A1 (0.32) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL9180441 0.75 ALDH1A1 (0.46) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL5837930 0.75 ALDH1A1 (0.33) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL21450712 0.74 CYP3A4 (0.40) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL9184047 0.74 ALDH1A1 (0.40) ALDH1A1TP53CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022120907-A1 SILICA MODIFICATION METHOD, SILICA FILLER, AND EPOXY RESIN COMPOSITE MATERIAL 深圳先进技术研究院 2022-06-16 WO claimed
CN-114507417-A Modified epoxy resin and use method thereof 浙江豪邦化工有限公司 2022-05-17 CN claimed
EP-3621787-B1 METHOD OF BONDING METAL FITTINGS TO A POLYURETHANE STRUCTURE VINYL TECH INC (US) 2021-08-11 EP claimed
CN-112662011-A Modification method of silicon dioxide, silicon dioxide filler and epoxy resin composite material 深圳先进技术研究院 2021-04-16 CN claimed
US-10723083-B2 Polyurethane bonding process for fuel bladders VINYL TECHNOLOGY, INC. (US) 2020-07-28 US claimed
EP-3621787-A1 METHOD OF BONDING A METAL FITTING TO A POLYURETHANE STRUCTURE Vinyl Technology, Inc. (US) 2020-03-18 EP claimed
CN-110891771-A Method for bonding metal fittings to polyurethane structures 乙烯技术公司 2020-03-17 CN claimed
WO-2018209141-A1 METHOD OF BONDING A METAL FITTING TO A POLYURETHANE STRUCTURE VINYL TECHNOLOGY, INC. (US) 2018-11-15 WO claimed
US-20180326673-A1 POLYURETHANE BONDING PROCESS FOR FUEL BLADDERS VINYL TECHNOLOGY, INC. (US) 2018-11-15 US claimed
US-20060058492-A1 Polyisocyanate prepolymer component for preparing a polyurethane-polyurea polymer SPECIALTY PRODUCTS, INC. 2006-03-16 US claimed
US-20060058491-A1 Isocyanate-reactive component for preparing a polyurethane-polyurea polymer SPECIALTY PRODUCTS, INC. 2006-03-16 US claimed
US-20050287373-A1 Papermaking machine belt ICHIKAWA CO., LTD. 2005-12-29 US claimed
EP-1609905-A1 Papermaking machine belt and method for manufacturing a papermaking machine belt ICHIKAWA CO.,LTD. (JP) 2005-12-28 EP claimed
US-6538060-B2 Comprising: a bituminous material, polyol, curing agent chosen such that a gelation time no longer than 495 seconds, and an isocyanate URECOATS INTERNATIONAL, INC. 2003-03-25 US claimed
EP-0705287-B1 POLYUREAURETHANE PRIMERLESS STRUCTURAL ADHESIVE ASHLAND OIL INC (US) 2002-10-16 EP claimed
US-20010051676-A1 Bituminous polyurethane interpenetrating elastomeric network compositions as coatings and sealants for roofing and other applications URECOATS INTERNATIONAL, INC. 2001-12-13 US claimed
US-6271305-B1 POLYURETHANES WITH POLYETHERS AND CURING AGENTS URECOATS TECHNOLOGIES, INC. 2001-08-07 US claimed
EP-0434245-A2 Polyurea elastomer with rapid dry time TEXACO CHEMICAL COMPANY (US) 1991-06-26 EP claimed
JP-5078443-A None JP disclosed
US-4595742-A Formed by reacting polyisocyanate, an organic active hydrogen group containing compound, and a chain extender comprising an aromatic diamine ETHYL CORPORATION (US) 1986-06-17 US disclosed