Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13943436 | 0.99 | PLA2G2A (0.35) | PLA2G2APLA2G4APLA2G10PDE10AKDM4E | |
| SCHEMBL21101416 | 0.96 | PDE10A (0.35) | PDE10AKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL16687545 | 0.90 | PLA2G2A (0.33) | PLA2G2APLA2G4APLA2G10PDE10A | |
| SCHEMBL15976635 | 0.90 | CASP3 (0.34) | PDE10AKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL16687544 | 0.88 | PLA2G2A (0.33) | PLA2G2APLA2G4APLA2G10PDE10A | |
| SCHEMBL16366355 | 0.88 | PLA2G2A (0.33) | PLA2G2APLA2G4APLA2G10PDE10A | |
| SCHEMBL17570883 | 0.87 | MAPT (0.34) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL20709532 | 0.85 | PLA2G10 (0.30) | PLA2G2APLA2G4APLA2G10 | |
| SCHEMBL21101504 | 0.84 | MAPT (0.34) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL16366621 | 0.83 | PDE10A (0.32) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2993215-A1 | Azabenzimidazo[2,1-a]benzimidazoles for electronic applications | Idemitsu Kosan Co., Ltd. (JP) | 2016-03-09 | — | — | EP | disclosed |