Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17570826 | 0.96 | PLA2G2A (0.36) | PDE10ANPC1MAPTKDM4EMEN1 | |
| SCHEMBL13943436 | 0.94 | PLA2G2A (0.35) | PDE10ANPC1MAPTKDM4EMEN1 | |
| SCHEMBL15976635 | 0.92 | CASP3 (0.34) | PDE10ANPC1MAPTKDM4EMEN1 | |
| SCHEMBL17570883 | 0.91 | MAPT (0.34) | NPC1MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL16366355 | 0.88 | PLA2G2A (0.33) | PDE10A | |
| SCHEMBL16687544 | 0.88 | PLA2G2A (0.33) | PDE10A | |
| SCHEMBL26506334 | 0.86 | — | — | |
| SCHEMBL16687545 | 0.86 | PLA2G2A (0.33) | PDE10A | |
| SCHEMBL16366356 | 0.84 | PDE10A (0.32) | PDE10A | |
| SCHEMBL16366621 | 0.83 | PDE10A (0.32) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2993215-B1 | Azabenzimidazo[2,1-a]benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2019-06-19 | — | — | EP | disclosed |