Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 7/20 | 0.41 |
| ▸ | GSTM2 | P28161 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1076589 | 0.85 | MEN1 (0.60) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL3505281 | 0.81 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL17914175 | 0.79 | MEN1 (0.63) | MEN1KMT2AALDH1A1GSTP1GSTM2 | |
| SCHEMBL4439764 | 0.77 | MEN1 (0.54) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL7467184 | 0.76 | MEN1 (0.56) | MEN1KMT2AALDH1A1KCNH2GSTP1 | |
| SCHEMBL7463890 | 0.76 | NSD2 (0.62) | MEN1KMT2AL3MBTL1KCNH2GSTP1 | |
| SCHEMBL1484117 | 0.76 | MEN1 (0.66) | MEN1KMT2AMAPTL3MBTL1GSTP1 | |
| SCHEMBL6834711 | 0.75 | MEN1 (0.69) | MEN1KMT2AL3MBTL1GSTP1GSTM2 | |
| SCHEMBL25342264 | 0.75 | IDO1 (0.47) | MEN1KMT2AALDH1A1KCNH2GSTP1 | |
| SCHEMBL3016679 | 0.72 | MEN1 (0.49) | MEN1KMT2AKCNH2GSTP1GSTM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2993477-A1 | AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS | Enzo Life Sciences, Inc. (US) | 2016-03-09 | — | — | EP | disclosed |