SCHEMBL1076589

SCHEMBL1076589

CCN(CC)c1ccc([N+](=O)[O-])c2nonc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.60
▸ KMT2A Q03164 5/20 0.60
▸ MAPT P10636 3/20 0.57
▸ ALDH1A1 P00352 2/20 0.57
▸ MAPK1 P28482 1/20 0.57
▸ L3MBTL1 Q9Y468 1/20 0.57
▸ GSTP1 P09211 4/20 0.51
▸ GSTM2 P28161 4/20 0.51
▸ GAA P10253 2/20 0.49
▸ KCNH2 Q12809 1/20 0.48
▸ NPC1 O15118 1/20 0.48
▸ RAB9A P51151 1/20 0.48
▸ ALDH3A1 P30838 1/20 0.48
▸ IDO1 P14902 4/20 0.47
▸ HCAR3 P49019 1/20 0.47
▸ LMNA P02545 1/20 0.46
▸ USP2 O75604 2/20 0.46
▸ G6PD P11413 1/20 0.46
▸ CASP6 P55212 1/20 0.46
▸ HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3505281 0.90 MEN1 (0.59) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL17914175 0.87 MEN1 (0.63) MEN1KMT2AALDH1A1GSTP1GSTM2
SCHEMBL17571858 0.85 MEN1 (0.52) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL4439764 0.85 MEN1 (0.54) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL7467184 0.84 MEN1 (0.56) MEN1KMT2AALDH1A1GSTP1GSTM2
SCHEMBL7463890 0.84 NSD2 (0.62) MEN1KMT2AL3MBTL1GSTP1GSTM2
SCHEMBL6834711 0.83 MEN1 (0.69) MEN1KMT2AL3MBTL1GSTP1GSTM2
SCHEMBL6831372 0.81 MEN1 (0.70) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL12427044 0.80 MEN1 (0.47) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL1484117 0.80 MEN1 (0.66) MEN1KMT2AMAPTL3MBTL1GSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1346224-B1 METHOD FOR THE MANIPULATION OF MICROCARRIERS FOR AN IDENTIFICATION PURPOSE MYCARTIS N V (BE) 2017-03-01 — — EP disclosed
WO-2016083132-A1 METHOD FOR PRODUCING HIGH-VOLTAGE INSULATION SIEMENS AKTIENGESELLSCHAFT (DE) 2016-06-02 — — WO disclosed
EP-3026676-A1 Method for producing a high voltage insulation Siemens Aktiengesellschaft (DE) 2016-06-01 — — EP disclosed
US-20140249050-A1 METHOD AND DEVICE FOR THE MANIPULATION OF MICROCARRIERS FOR AN IDENTIFICATION PURPOSE BIOCARTIS SA (CH) 2014-09-04 — — US disclosed
US-8772048-B2 Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems KENT STATE UNIVERSITY (US) 2014-07-08 — — US disclosed
US-8772048-B2 Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems KENT STATE UNIVERSITY (US) 2014-07-08 — — US disclosed
US-8735172-B2 Method and device for the manipulation of microcarriers for an identification purpose BIOCARTIS S.A. (CH) 2014-05-27 — — US disclosed
US-20120190098-A1 FLUOROGENIC COMPOUNDS CONVERTED TO FLUOROPHORES BY PHOTOCHEMICAL OR CHEMICAL MEANS AND THEIR USE IN BIOLOGICAL SYSTEMS LELAND STANFORD JUNIOR UNIVERSITY (US) 2012-07-26 — — US disclosed
US-20120190098-A1 FLUOROGENIC COMPOUNDS CONVERTED TO FLUOROPHORES BY PHOTOCHEMICAL OR CHEMICAL MEANS AND THEIR USE IN BIOLOGICAL SYSTEMS LELAND STANFORD JUNIOR UNIVERSITY (US) 2012-07-26 — — US disclosed
US-8153446-B2 Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems KENT STATE UNIVERSITY (US) 2012-04-10 — — US disclosed
US-8153446-B2 Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems KENT STATE UNIVERSITY (US) 2012-04-10 — — US disclosed
US-20110082046-A1 METHOD AND DEVICE FOR THE MANIPULATION OF MICROCARRIERS FOR AN IDENTIFICATION PURPOSE UNIVERSITEIT GENT (BE) 2011-04-07 — — US disclosed
EP-2275819-A2 Method and device for the manipulation of microcarriers for an identification purpose Biocartis SA (CH) 2011-01-19 — — EP disclosed
US-20100029952-A1 Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems KENT STATE UNIVERSITY (US) 2010-02-04 — — US disclosed
US-20100029952-A1 Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems KENT STATE UNIVERSITY (US) 2010-02-04 — — US disclosed
US-20040069857-A1 Method and device for the manipulation of microcarriers for an identification purpose TIBOTEC (BE) 2004-04-15 — — US disclosed
EP-1346224-A1 METHOD AND DEVICE FOR THE MANIPULATION OF MICROCARRIERS FOR AN IDENTIFICATION PURPOSE Tibotec BVBA (BE) 2003-09-24 — — EP disclosed
WO-2002033419-A1 METHOD AND DEVICE FOR THE MANIPULATION OF MICROCARRIERS FOR AN IDENTIFICATION PURPOSE TIBOTEC BVBA (BE) 2002-04-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120190098-A1 FLUOROGENIC COMPOUNDS CONVERTED TO FLUOROPHORES BY PHOTOCHEMICAL OR CHEMICAL MEANS AND THEIR USE IN BIOLOGICAL SYSTEMS MPI, ACR, PFAS MEN1 1973/4885KMT2A 4469/4885MAPT 2134/4885
US-20100029952-A1 Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems MPI, ACR, PFAS MEN1 1973/4885KMT2A 4469/4885MAPT 2134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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