Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.48 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.48 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GSTM2 | P28161 | 11/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 10/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3505281 | 0.85 | MEN1 (0.59) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL7463890 | 0.85 | NSD2 (0.62) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL1076589 | 0.84 | MEN1 (0.60) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL4439764 | 0.81 | MEN1 (0.54) | MEN1KMT2AUSP2KCNH2GSTM2 | |
| SCHEMBL7052057 | 0.79 | GSTM2 (0.66) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL6834711 | 0.78 | MEN1 (0.69) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL17914175 | 0.77 | MEN1 (0.63) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL17571858 | 0.76 | MEN1 (0.52) | MEN1KMT2AUSP2KCNH2GSTM2 | |
| SCHEMBL1484117 | 0.76 | MEN1 (0.66) | MEN1KMT2AUSP2POLBTNNI3 | |
| SCHEMBL4942785 | 0.74 | MEN1 (0.56) | MEN1KMT2AGSTM2GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |