Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 9/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15157223 | 0.81 | PTP4A3 (0.41) | ARP4HB | |
| SCHEMBL15157445 | 0.80 | KIF11 (0.50) | — | |
| SCHEMBL3890018 | 0.79 | P4HB (0.44) | RXRARXRBRXRGARSCN9A | |
| SCHEMBL6029975 | 0.79 | P4HB (0.44) | RXRARXRBRXRGARSCN9A | |
| SCHEMBL16682648 | 0.79 | KIF11 (0.47) | ARSLC22A12 | |
| SCHEMBL31173121 | 0.79 | KIF11 (0.47) | ARSLC22A12 | |
| SCHEMBL15157679 | 0.78 | NPFFR1 (0.40) | — | |
| SCHEMBL12497484 | 0.78 | CYP11B2 (0.43) | — | |
| SCHEMBL13358948 | 0.77 | NR3C2 (0.40) | AR | |
| SCHEMBL15157365 | 0.75 | NPFFR2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2809669-B1 | FUSED PYRROLEDICARBOXAMIDES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-02-01 | — | — | EP | disclosed |
| US-9284333-B2 | Fused pyrroledicarboxamides and their use as pharmaceuticals | SANOFI (FR) | 2016-03-15 | — | — | US | disclosed |