Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | EYA2 | O00167 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431521 | 0.97 | TDP1 (0.55) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL429048 | 0.95 | TDP1 (0.50) | TDP1EYA2APPACEKDM4E | |
| Hydrochloric Acid SCHEMBL8981614 | 0.92 | TDP1 (0.48) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL5922611 | 0.91 | TDP1 (0.42) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL8855492 | 0.91 | TDP1 (0.42) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL10326051 | 0.88 | TDP1 (0.64) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL15210188 | 0.87 | TDP1 (0.39) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL26558171 | 0.86 | TDP1 (0.42) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL89280 | 0.84 | TDP1 (0.46) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL20819248 | 0.84 | TDP1 (0.41) | TDP1EYA2APPACEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1789 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507303-A | External electron donor for olefin polymerization, catalyst system and olefin polymerization method | 中国石油化工股份有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-114478870-A | Catalyst system for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114502153-A | Compositions for inhibiting SRC kinase and treating and preventing related disorders | 恩泽生物科学有限公司 | 2022-05-13 | — | — | CN | claimed |
| WO-2021053493-A1 | COMPOSITIONS FOR USE IN INHIBITING SRC KINASE AND TREATING AND PREVENTING ASSOCIATED DISORDERS | ENZENE BIOSCIENCES LIMITED (IN) | 2021-03-25 | — | — | WO | claimed |
| US-20210085633-A1 | RIVASTIGMINE-CONTAINING TRANSDERMAL ABSORPTION PREPARATION | TEIKOKU SEIYAKU CO., LTD. (JP) | 2021-03-25 | — | — | US | claimed |
| EP-3656383-A1 | RIVASTIGMINE-CONTAINING PERCUTANEOUS ABSORPTION-TYPE PREPARATION | Teikoku Seiyaku Co., Ltd. (JP) | 2020-05-27 | — | — | EP | claimed |
| US-10369102-B2 | Wax foamable vehicle and pharmaceutical compositions thereof | FOAMIX PHARMACEUTICALS LTD. (IL) | 2019-08-06 | — | — | US | claimed |
| CN-107602401-A | A kind of method for preparing spices geraniol | 江西凡生实业有限公司 | 2018-01-19 | — | — | CN | claimed |
| US-20180000734-A1 | Wax Foamable Vehicle and Pharmaceutical Compositions Thereof | VYNE THERAPEUTICS INC. (F/K/A MENLO THERAPEUTICS INC. AND SUCCESSOR-IN-INTEREST TO VYNE PHARMACEUTICALS LTD., F/K/A FOAMIX PHARMACEUTICALS LTD.) | 2018-01-04 | — | — | US | claimed |
| WO-2017191532-A1 | PHARMACEUTICAL FOAM COMPOSITION | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-11-09 | — | — | WO | claimed |
| US-6573299-B1 | Prevention and treatment of orbital disorders associated with the aging eye in mammals by the application of a topical composition comprising a permeation enhancing amount of one or more penetration enhancers, and one or more bio-affecting | ADVANCED MEDICAL INSTRUMENTS | 2003-06-03 | — | — | US | claimed |
| US-6399093-B1 | ANTIINFLAMMATORY AGENTS AND COLCHICINE FOR TISSUES | ADVANCED MEDICAL INSTRUMENTS | 2002-06-04 | — | — | US | claimed |
| US-5604294-A | IMMUNOSUPRESSIVE, ANTIMICROBIAL, ANTIFUNGAL, ANTIVIRAL, ANTI-INFLAMMATORY AND ANTIPROLIFERATIVE ACTIVITY | ABBOTT LABORATORIES | 1997-02-18 | — | — | US | claimed |
| US-5599927-A | HETEROCYCLIC RING, AMINO-, AMIDO- OR ISOCYANAT-ALKYL SUBSTITUTED IMMUNOSUPPRESSANTS; SIDE-EFFECT REDUCTION | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| US-5541189-A | Substituted aliphatic amine-containing macrocyclic immunomodulators | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | claimed |
| US-5541193-A | ORGAN TRANSPLANTS | ABBOTT LABORATORIES (US) | 1996-07-30 | — | — | US | claimed |
| US-5457111-A | Side effect reduction | ABBOTT LABORATORIES (US) | 1995-10-10 | — | — | US | claimed |
| US-5457194-A | Immunosuppressants | ABBOTT LABORATORIES (US) | 1995-10-10 | — | — | US | claimed |
| EP-0342558-B1 | 2-amino-4,5-methyleneadipic acid compounds for treatment of CNS disorders | SEARLE & CO (US) | 1994-02-02 | — | — | EP | claimed |
| US-4426375-A | DIALLYLAMINE DERIVATIVES | L'OREAL (FR) | 1984-01-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180000734-A1 | Wax Foamable Vehicle and Pharmaceutical Compositions Thereof | CUTA, LIPA, MGLL | TDP1 426/4885EYA2 136/4885APP 12/4885 |
| US-10369102-B2 | Wax foamable vehicle and pharmaceutical compositions thereof | CUTA, LIPA, MGLL | TDP1 426/4885EYA2 136/4885APP 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.