SCHEMBL89280

SCHEMBL89280

C=CCN(CCO)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.46
EYA2 O00167 1/20 0.46
APP P05067 1/20 0.46
ACE P12821 1/20 0.46
KDM4E B2RXH2 8/20 0.44
BLM P54132 2/20 0.44
PMP22 Q01453 2/20 0.44
ALOX15 P16050 2/20 0.44
LMNA P02545 2/20 0.44
CHRM2 P08172 1/20 0.44
ADRA2A P08913 1/20 0.44
TSHR P16473 1/20 0.44
DRD1 P21728 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
CYP2C19 P33261 1/20 0.44
ADRA1A P35348 1/20 0.44
DRD3 P35462 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10326051 0.87 TDP1 (0.64) TDP1EYA2APPACEKDM4E
SCHEMBL175747 0.84 TDP1 (0.50) TDP1EYA2APPACEKDM4E
SCHEMBL429048 0.84 TDP1 (0.50) TDP1EYA2APPACEKDM4E
SCHEMBL431521 0.82 TDP1 (0.55) TDP1EYA2APPACEKDM4E
Hydrochloric Acid SCHEMBL8981614 0.82 TDP1 (0.48) TDP1EYA2APPACEKDM4E
SCHEMBL1049790 0.82 TDP1 (0.44) TDP1EYA2APPACEKDM4E
SCHEMBL15955451 0.81 KDM4E (0.31) KDM4EKMT2AMEN1SMN1; SMN2
Acetic Acid SCHEMBL2866049 0.81 KDM4E (0.38) TDP1KDM4EALOX15LMNAKMT2A
SCHEMBL28550794 0.80 TDP1 (0.48) TDP1EYA2APPACEKDM4E
SCHEMBL28110603 0.80 TDP1 (0.43) TDP1EYA2APPACEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104585228-A MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS MONSANTO TECHNOLOGY LLC 2015-05-06 CN claimed
EP-1853115-A2 MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS Monsanto Technology, LLC (US) 2007-11-14 EP claimed
WO-2006096617-A2 MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS MONSANTO TECHNOLOGY LLC (US) 2006-09-14 WO claimed
US-20230102424-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations MONSANTO TECHNOLOGY LLC 2023-03-30 US disclosed
US-20200236930-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations MONSANTO TECHNOLOGY LLC (US) 2020-07-30 US disclosed
EP-1853115-B1 MITIGATING NECROSIS IN TRANSGENIC GLYPHOSATE-TOLERANT COTTON PLANTS TREATED WITH HERBICIDAL GLYPHOSATE FORMULATIONS MONSANTO TECHNOLOGY LLC (US) 2019-01-09 EP disclosed
US-20170339950-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations MONSANTO TECHNOLOGY LLC (US) 2017-11-30 US disclosed
CN-104585228-B Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations 孟山都技术公司 2017-05-24 CN disclosed
US-9642359-B2 Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations MONSANTO TECHNOLOGY LLC (US) 2017-05-09 US disclosed
US-20160330956-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations MONSANTO TECHNOLOGY LLC (US) 2016-11-17 US disclosed
US-9364003-B2 Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations MONSANTO TECHNOLOGY LLC (US) 2016-06-14 US disclosed
EP-0554007-B1 Catalytic synthesis of alkyl morpholinones HUNTSMAN CORP (US) 1998-05-27 EP disclosed
EP-0425929-B1 Process for the preparation of N-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxy-piperidine and of intermediates BAYER AG (DE) 1995-12-06 EP disclosed
EP-0554007-A1 Catalytic synthesis of alkyl morpholinones Huntsman Corporation (US) 1993-08-04 EP disclosed
US-5136035-A Catalytic synthesis of alkyl morpholinones TEXACO CHEMICAL COMPANY (US) 1992-08-04 US disclosed
EP-0217250-B1 FOAMING SURFACTANT PREPARATIONS WITH CLEAR, SOLUBILIZED WATER INSOLUBLE OIL COMPONENTS Henkel Kommanditgesellschaft auf Aktien (DE) 1992-04-08 EP disclosed
EP-0288919-B1 GELLED FOAM BATH CONCENTRATE Henkel Kommanditgesellschaft auf Aktien (DE) 1992-03-04 EP disclosed
US-5071990-A PREPARATION OF INTERMEDIATES AND THE SYNTHESIS OF N-(2-HYDROXYETHYL)-2-HYDROXYMETHYL-3,4,5-TRIHYDROXYPIPERIDINES BAYER AKTIENGESELLSCHAFT (DE) 1991-12-10 US disclosed
US-5066804-A Preparation of alkyl morpholinones TEXACO CHEMICAL COMPANY (US) 1991-11-19 US disclosed
EP-0217250-A2 Foaming surfactant preparations with clear, solubilized water insoluble oil components Henkel Kommanditgesellschaft auf Aktien (DE) 1987-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200236930-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations GLO1, AGXT, GRHPR TDP1 681/4885EYA2 2368/4885APP 2809/4885
US-20170339950-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations GLO1, AGXT, GRHPR TDP1 681/4885EYA2 2368/4885APP 2809/4885
US-20230102424-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations GLO1, AGXT, GRHPR TDP1 681/4885EYA2 2368/4885APP 2809/4885
US-20160330956-A1 Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations GLO1, AGXT, GRHPR TDP1 681/4885EYA2 2368/4885APP 2809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.