Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.39 |
| ▸ | BCL2 | P10415 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 6/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3516836 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4EMCL1BCL2HPGD | |
| SCHEMBL175752 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4EMCL1BCL2HPGD | |
| Hydrochloric Acid SCHEMBL7300448 | 0.98 | ALDH1A1 (0.41) | ALDH1A1KDM4EMCL1BCL2HPGD | |
| SCHEMBL7288378 | 0.84 | PIK3CA (0.36) | ALDH1A1KDM4ESCN1ASCN5ASCN8A | |
| SCHEMBL6211278 | 0.83 | SCN9A (0.35) | ALDH1A1KDM4ESCN1ASCN5ASCN8A | |
| SCHEMBL6616473 | 0.83 | SCN9A (0.35) | ALDH1A1KDM4ESCN1ASCN5ASCN8A | |
| Hydrochloric Acid SCHEMBL6498236 | 0.81 | SCN9A (0.34) | ALDH1A1KDM4ESCN1ASCN5ASCN8A | |
| Gabapentin SCHEMBL3169310 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4EMCL1BCL2HPGD | |
| SCHEMBL7299956 | 0.76 | KDM4E (0.35) | ALDH1A1KDM4EHPGDSCN1ASCN5A | |
| SCHEMBL9217841 | 0.74 | FPR2 (0.32) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 725 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4127157-B1 | MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS | ENCODIA INC (US) | 2026-02-11 | — | — | EP | claimed |
| EP-4650362-A1 | NEUROPROTECTIVE PSD-95 POLYPEPTIDE INHIBITOR AND USE THEREOF | Beijing Tuo Jie Biopharmaceutical Co. Ltd. (CN) | 2025-11-19 | — | — | EP | claimed |
| CN-119158034-A | Bicyclic peptide ligands specific for conjugated protein-4 | 拜斯科技术开发有限公司 | 2024-12-20 | — | — | CN | claimed |
| WO-2024149230-A1 | NEUROPROTECTIVE PSD-95 POLYPEPTIDE INHIBITOR AND USE THEREOF | 北京拓界生物医药科技有限公司 | 2024-07-18 | — | — | WO | claimed |
| WO-2024030977-A2 | NOVEL MELANOCORTIN ANALOGS | SIGHTSTREAM BIOTHERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | claimed |
| US-20240011009-A1 | MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS | Encodia, Inc. (US) | 2024-01-11 | — | — | US | claimed |
| EP-4274597-A1 | METHODS FOR TREATING CANCER | BicycleTX Limited (GB) | 2023-11-15 | — | — | EP | claimed |
| US-20230220589-A1 | POLYPEPTIDE TERMINAL BINDERS AND USES THEREOF | Encodia, Inc. (US) | 2023-07-13 | — | — | US | claimed |
| EP-4127157-A1 | MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS | Encodia, Inc. (US) | 2023-02-08 | — | — | EP | claimed |
| US-20220306692-A1 | PEPTIDE INHIBITORS OF FOCAL ADHESION KINASE ACTIVITY AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2022-09-29 | — | — | US | claimed |
| WO-1996040741-A1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-12-19 | — | — | WO | claimed |
| WO-1996040742-A1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATEDDISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-12-19 | — | — | WO | claimed |
| US-5523308-A | SERINE PROTEASES INHIBITORS; ORAL ANTICOAGULANTS; CHEMICAL INTERMEDIATES; DIPEPTIDES | ORTHO PHARMACEUTICAL CORPORATION | 1996-06-04 | — | — | US | claimed |
| EP-0373549-B1 | AMINO ACID DERIVATIVES WITH ENZYME-INHIBITING PROPERTIES, PROCESS TO SYNTHETISE THEM, COMPOSITION CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-01 | — | — | EP | claimed |
| WO-1992007845-A1 | DERIVATIVES OF AMINO ACIDS AS INHIBITORS OF RENIN, METHODS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-14 | — | — | WO | claimed |
| EP-0483403-A1 | Derivatives of amino acids as inhibitors of renin, methods for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-06 | — | — | EP | claimed |
| EP-0417698-A2 | Amino acid derivatives having renin-inhibiting activity, process for their preparation, agents containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-20 | — | — | EP | claimed |
| EP-0373549-A2 | Amino acid derivatives with enzyme-inhibiting properties, process to synthetise them, composition containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | claimed |
| EP-0372537-A2 | Urea derivatives of dipeptides with enzyme-inhibiting properties, process to make them, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-13 | — | — | EP | claimed |
| EP-0370383-A2 | Renin-inhibiting dipeptides, process to make them, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306692-A1 | PEPTIDE INHIBITORS OF FOCAL ADHESION KINASE ACTIVITY AND USES THEREOF | PTK2, LTK, LIMK2 | ALDH1A1 4793/4885KDM4E 3767/4885MCL1 3083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.