Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | NPR3 | P17342 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616473 | 0.80 | SCN9A (0.35) | FPR2SCN9A | |
| SCHEMBL6211278 | 0.80 | SCN9A (0.35) | FPR2SCN9A | |
| Hydrochloric Acid SCHEMBL6498236 | 0.79 | SCN9A (0.34) | FPR2SCN9A | |
| SCHEMBL3516836 | 0.74 | ALDH1A1 (0.42) | SCN9A | |
| SCHEMBL175752 | 0.74 | ALDH1A1 (0.42) | SCN9A | |
| SCHEMBL175753 | 0.74 | ALDH1A1 (0.42) | SCN9A | |
| SCHEMBL7288378 | 0.72 | PIK3CA (0.36) | FPR2SCN9A | |
| Hydrochloric Acid SCHEMBL7300448 | 0.72 | ALDH1A1 (0.41) | SCN9A | |
| SCHEMBL165039 | 0.71 | ATR (0.40) | SCN9ACCNB2CCNE2CDK1CDK4 | |
| SCHEMBL9297590 | 0.71 | GLS (0.46) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378689-A | Hypotensive agents; administrable by mouth | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |