Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17577149 | 0.89 | HCAR2 (0.38) | THRBHCAR2ALDH1A1TGM2LMNA | |
| SCHEMBL29577996 | 0.83 | THRB (0.53) | THRBTHRAHCAR2TSHRALDH1A1 | |
| SCHEMBL10451653 | 0.83 | THRB (0.53) | THRBTHRAHCAR2TSHRALDH1A1 | |
| SCHEMBL8692638 | 0.83 | THRB (0.47) | THRBHCAR2TSHRFABP7FABP3 | |
| SCHEMBL27421526 | 0.82 | THRB (0.45) | THRBTHRATYMSHCAR2TSHR | |
| SCHEMBL29484778 | 0.79 | MEN1 (0.51) | THRBALDH1A1TGM2NPSR1NPC1 | |
| SCHEMBL2167443 | 0.79 | MEN1 (0.51) | THRBALDH1A1TGM2NPSR1NPC1 | |
| SCHEMBL25403889 | 0.78 | THRB (0.43) | THRBHCAR2TSHRALDH1A1LMNA | |
| SCHEMBL960201 | 0.77 | IDO1 (0.48) | THRBTHRAHCAR2TSHRALDH1A1 | |
| SCHEMBL9555275 | 0.77 | THRB (0.47) | THRBTHRAHCAR2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9594318-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-03-14 | — | — | US | disclosed |
| US-20160070184-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-03-10 | — | — | US | disclosed |