Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17577134 | 0.89 | THRB (0.43) | HCAR2LMNATHRBFFAR1FFAR4 | |
| SCHEMBL19730199 | 0.81 | HCAR2 (0.47) | HCAR2LMNATHRBAKR1B10AKR1B1 | |
| SCHEMBL17577135 | 0.78 | TSHR (0.45) | HCAR2LMNATHRBAKR1B10AKR1B1 | |
| SCHEMBL8692638 | 0.77 | THRB (0.47) | HCAR2THRBFFAR1FFAR4 | |
| SCHEMBL2435314 | 0.76 | HCAR2 (0.53) | HCAR2LMNATHRBFFAR1AKR1B10 | |
| SCHEMBL19730238 | 0.76 | AKR1B10 (0.48) | HCAR2LMNATHRBAKR1B10AKR1B1 | |
| SCHEMBL12367978 | 0.76 | HCAR2 (0.46) | HCAR2LMNATHRBAKR1B10AKR1B1 | |
| SCHEMBL16125662 | 0.76 | HCAR2 (0.46) | HCAR2LMNATHRBAKR1B10AKR1B1 | |
| SCHEMBL17577127 | 0.75 | HCAR2 (0.42) | HCAR2LMNATHRBFFAR1FFAR4 | |
| SCHEMBL17577122 | 0.75 | AKR1B10 (0.40) | HCAR2LMNATHRBAKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9594318-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-03-14 | — | — | US | disclosed |
| US-20160070184-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-03-10 | — | — | US | disclosed |