Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 10/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17577168 | 0.93 | TSHR (0.49) | TSHRTHRATHRBRARBRARA | |
| SCHEMBL17578320 | 0.90 | TSHR (0.40) | TSHRTHRATHRBRARBRARA | |
| SCHEMBL17577132 | 0.85 | THRB (0.44) | TSHRTHRATHRBRARBRARA | |
| SCHEMBL17577140 | 0.85 | THRB (0.44) | TSHRTHRATHRBRARBRARA | |
| SCHEMBL17577133 | 0.82 | POLB (0.36) | TSHRTHRATHRBRARB | |
| SCHEMBL17577136 | 0.80 | RXRA (0.33) | TSHR | |
| SCHEMBL17578319 | 0.79 | THRB (0.43) | TSHRTHRATHRBRARBRARA | |
| SCHEMBL3176037 | 0.78 | THRB (0.61) | TSHRTHRATHRBRARBRARA | |
| SCHEMBL3176142 | 0.78 | THRB (0.61) | TSHRTHRATHRBRARBRARA | |
| SCHEMBL3178741 | 0.78 | THRB (0.61) | TSHRTHRATHRBRARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9594318-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-03-14 | — | — | US | disclosed |
| US-20160070184-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-03-10 | — | — | US | disclosed |