SCHEMBL17577288

SCHEMBL17577288

OBOc1ccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
LTA4H P09960 1/20 0.31
NR1H2 P55055 1/20 0.31
BAX Q07812 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12014943 0.84 ESR1 (0.39) ESR1ESR2NR1H2
SCHEMBL3189953 0.83 ESR1 (0.31) ESR1ESR2LTA4H
SCHEMBL11978730 0.82 CYP4F2 (0.31) LTA4H
SCHEMBL103797 0.79
SCHEMBL12045432 0.79 CA2 (0.44)
SCHEMBL7129361 0.77 LTA4H (0.43) LTA4HNR1H2BAX
SCHEMBL14477632 0.76 MEN1 (0.33) ESR1ESR2
SCHEMBL410120 0.76 LTA4H (0.57) LTA4HNR1H2BAX
SCHEMBL819908 0.76 MMP3 (0.44) ESR1ESR2
SCHEMBL12879524 0.74 ESR1 (0.43) ESR1ESR2LTA4HNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160072072-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160072072-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CCNE2, CCNL2, CCNT1 ESR1 45/4885ESR2 199/4885LTA4H 1136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.