Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.51 |
| ▸ | NOS3 | P29474 | 5/20 | 0.51 |
| ▸ | NOS1 | P29475 | 5/20 | 0.51 |
| ▸ | NOS2 | P35228 | 5/20 | 0.51 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701037 | 0.96 | NOS3 (0.50) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL701038 | 0.96 | NOS3 (0.50) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL701039 | 0.96 | NOS3 (0.50) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL6675526 | 0.94 | NOS3 (0.49) | TAS1R3TAS1R1NOS3NOS1NOS2 | |
| SCHEMBL17559257 | 0.85 | PLA2G2A (0.51) | TAS1R3TAS1R1FOLH1 | |
| SCHEMBL17559259 | 0.85 | PLA2G2A (0.51) | TAS1R3TAS1R1FOLH1 | |
| SCHEMBL5272358 | 0.81 | PLA2G2A (0.54) | SMN1; SMN2 | |
| SCHEMBL15285201 | 0.80 | PLA2G2A (0.56) | SMN1; SMN2 | |
| SCHEMBL6673373 | 0.80 | PLA2G2A (0.56) | SMN1; SMN2 | |
| SCHEMBL6674099 | 0.80 | PLA2G2A (0.56) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016037072-A2 | ENOPEPTIN ANALOGAS AND METHODS OF USE THEREOF | BROWN UNIVERSITY (US) | 2016-03-10 | — | — | WO | disclosed |