Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.51 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17559257 | 1.00 | PLA2G2A (0.51) | PLA2G2APLA2G5ALDH1A1MEN1LMNA | |
| SCHEMBL5272358 | 0.95 | PLA2G2A (0.54) | PLA2G2APLA2G5ALDH1A1MEN1LMNA | |
| SCHEMBL6674099 | 0.94 | PLA2G2A (0.56) | PLA2G2APLA2G5ALDH1A1MEN1LMNA | |
| SCHEMBL6673369 | 0.94 | PLA2G2A (0.56) | PLA2G2APLA2G5ALDH1A1MEN1LMNA | |
| SCHEMBL1681183 | 0.94 | PLA2G2A (0.56) | PLA2G2APLA2G5ALDH1A1MEN1LMNA | |
| SCHEMBL6673373 | 0.94 | PLA2G2A (0.56) | PLA2G2APLA2G5ALDH1A1MEN1LMNA | |
| SCHEMBL15285201 | 0.94 | PLA2G2A (0.56) | PLA2G2APLA2G5ALDH1A1MEN1LMNA | |
| SCHEMBL19279402 | 0.85 | ALDH1A1 (0.46) | PLA2G2APLA2G5ALDH1A1MEN1LMNA | |
| SCHEMBL17577957 | 0.85 | TAS1R3 (0.51) | TAS1R3TAS1R1FOLH1 | |
| SCHEMBL31027099 | 0.84 | CNR1 (0.60) | PLA2G2APLA2G5PLA2G10CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016037072-A2 | ENOPEPTIN ANALOGAS AND METHODS OF USE THEREOF | BROWN UNIVERSITY (US) | 2016-03-10 | — | — | WO | disclosed |