Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SCN1A | P35498 | 3/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990318 | 0.82 | L3MBTL1 (0.43) | L3MBTL1LMNAPOLBHTTSCN1A | |
| SCHEMBL11434362 | 0.82 | CASR (0.40) | L3MBTL1LMNAPOLBHTTSCN1A | |
| SCHEMBL28444789 | 0.81 | MEN1 (0.47) | L3MBTL1HTR2ACYP1A2CYP2D6TSHR | |
| SCHEMBL22394293 | 0.76 | CHRNA7 (0.39) | L3MBTL1 | |
| SCHEMBL22394310 | 0.76 | CHRNA7 (0.39) | L3MBTL1 | |
| SCHEMBL22394297 | 0.76 | KMT2A (0.39) | LMNAHTR2AHRH1MIFTSHR | |
| SCHEMBL6972092 | 0.74 | L3MBTL1 (0.42) | L3MBTL1LMNAPOLBHTTSCN1A | |
| SCHEMBL11830699 | 0.73 | AKR1C3 (0.41) | L3MBTL1LMNAPOLBTSHRMAPT | |
| SCHEMBL27491659 | 0.73 | L3MBTL1 (0.39) | L3MBTL1LMNACYP1A2SLC6A2SLC6A4 | |
| SCHEMBL3992907 | 0.73 | SCN1A (0.55) | L3MBTL1LMNAPOLBHTTSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2994451-A1 | ESTER DERIVATIVES OF ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | British Columbia Cancer Agency Branch (CA) | 2016-03-16 | — | — | EP | disclosed |