Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17580927 | 0.88 | HTR6 (0.46) | HTR6HTR2ACHRM1GRM5CHRNB2 | |
| SCHEMBL9902745 | 0.87 | HTR6 (0.66) | HTR6HTR2AGRM5FGFR4POLB | |
| SCHEMBL17580996 | 0.85 | HTR6 (0.43) | HTR6HTR2ACHRM1GRM5CHRNB2 | |
| SCHEMBL17580741 | 0.85 | HTR6 (0.43) | HTR6HTR2ACHRM1GRM5CHRNB2 | |
| SCHEMBL17580617 | 0.84 | HTR6 (0.42) | HTR6HTR2ACHRM1GRM5ALK | |
| SCHEMBL17580720 | 0.84 | HTR6 (0.42) | HTR6HTR2ACHRM1GRM5ALK | |
| SCHEMBL17580677 | 0.82 | HTR6 (0.41) | HTR6HTR2ACHRM1GRM5ALK | |
| SCHEMBL17580721 | 0.82 | HTR6 (0.42) | HTR6HTR2AGRM5CHRNB2CHRNA7 | |
| SCHEMBL17580675 | 0.82 | HTR6 (0.44) | HTR6HTR2ACHRM1GRM5ALK | |
| SCHEMBL9902830 | 0.82 | HTR6 (0.48) | HTR6HTR2AGRM5ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185555-B1 | QUINOLINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR | ABBVIE DEUTSCHLAND (DE) | 2016-03-16 | — | — | EP | claimed |