Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | FABP3 | P05413 | 1/20 | 0.53 |
| ▸ | FABP4 | P15090 | 1/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282772 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL9650199 | 0.83 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL28357168 | 0.81 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL29489100 | 0.81 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL30343301 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11455551 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL29688785 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9368516 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL3403656 | 0.78 | KMO (0.57) | KDM4EALDH1A1HPGD | |
| SCHEMBL30996109 | 0.78 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160090383-A1 | ANTIBACTERIAL PHTHALIDE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2016-03-31 | — | — | US | disclosed |
| EP-2994466-A1 | ANTIBACTERIAL PHTHALIDE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2016-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090383-A1 | ANTIBACTERIAL PHTHALIDE DERIVATIVES | MRPL21, MAPRE1, HDAC6 | KDM4E 1799/4885ALDH1A1 771/4885HPGD 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.