Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL1758356

O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F.[Sr+2]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ATP4AATP4B

The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.38
CA2 P00918 1/20 0.37
CA1 P00915 2/20 0.33
CASP1 P29466 1/20 0.33
FAHD1 Q6P587 1/20 0.33
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL4528375 0.92 CA4 (0.38) CA4CA2CA1CASP1FAHD1
Trifluoroacetic Acid SCHEMBL2828447 0.92 CA4 (0.38) CA4CA2CA1CASP1FAHD1
Trifluoroacetic Acid SCHEMBL108536 0.92
Trifluoroacetic Acid SCHEMBL20569310 0.92
Trifluoroacetic Acid SCHEMBL20571141 0.92 CA4 (0.38) CA4CA2CA1CASP1FAHD1
Trifluoroacetic Acid SCHEMBL4342494 0.92 CA4 (0.38) CA4CA2CA1CASP1FAHD1
Trifluoroacetic Acid SCHEMBL4398806 0.92
Trifluoroacetic Acid SCHEMBL20569660 0.92 CA4 (0.38) CA4CA2CA1CASP1FAHD1
Trifluoroacetic Acid SCHEMBL20541013 0.92 CA4 (0.38) CA4CA2CA1CASP1FAHD1
Trifluoroacetic Acid SCHEMBL18797016 0.92 CA4 (0.38) CA4CA2CA1CASP1FAHD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116426277-B Pure green up-conversion luminescent nano material and preparation method thereof 浙江大学 2024-01-09 CN claimed
CN-116426277-A Pure green up-conversion luminescent nano material and preparation method thereof 浙江大学 2023-07-14 CN claimed
CN-114381266-B Dynamic fluorescent lighting material and preparation method thereof 中国计量大学上虞高等研究院有限公司 2023-05-16 CN claimed
CN-110846037-B Up-conversion luminescent material and core-shell type fluorescent nano material with up-conversion luminescence and down-conversion long afterglow luminescence 杭州安旭生物科技股份有限公司 2023-02-28 CN claimed
CN-112457849-B Near-infrared fluoride core-shell nanocrystalline scintillator 中国计量大学 2022-08-09 CN claimed
CN-114381266-A Dynamic fluorescent lighting material and preparation method thereof 中国计量大学上虞高等研究院有限公司 2022-04-22 CN claimed
CN-114163992-A High-quantum-efficiency green light up-conversion core-shell nanocrystal and preparation method thereof 中国计量大学 2022-03-11 CN claimed
CN-112457849-A Near-infrared fluoride core-shell nanocrystalline scintillator 中国计量大学 2021-03-09 CN claimed
CN-107267149-B Red up-conversion luminescent nano material and preparation method thereof 中国科学院苏州纳米技术与纳米仿生研究所 2020-03-27 CN claimed
CN-110846037-A Up-conversion luminescent material and core-shell type fluorescent nano material with up-conversion luminescence and down-conversion long afterglow luminescence 杭州安旭生物科技股份有限公司 2020-02-28 CN claimed
US-6774088-B2 Rare earth-Ba-Cu complex composition and method of producing superconductor using same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2004-08-10 US claimed
US-20020139960-A1 Rare earth-Ba-Cu complex composition and method of producing superconductor using same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 2002-10-03 US claimed
CN-116426277-B Pure green up-conversion luminescent nano material and preparation method thereof 浙江大学 2024-01-09 CN disclosed
US-11814348-B2 Oxidizing liquid media for chemical transformations UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-11-14 US disclosed
CN-116426277-A Pure green up-conversion luminescent nano material and preparation method thereof 浙江大学 2023-07-14 CN disclosed
CN-114381266-B Dynamic fluorescent lighting material and preparation method thereof 中国计量大学上虞高等研究院有限公司 2023-05-16 CN disclosed
US-20120215008-A1 Process for the Preparation of 4-Sulfinyl-Pyrazole Derivatives BASF SE (DE) 2012-08-23 US disclosed
WO-2011051284-A1 PROCESS FOR THE PREPARATION OF 4-SULFINYL-PYRAZOLE DERIVATIVES BASF SE (DE) 2011-05-05 WO disclosed
US-6774088-B2 Rare earth-Ba-Cu complex composition and method of producing superconductor using same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2004-08-10 US disclosed
US-20020139960-A1 Rare earth-Ba-Cu complex composition and method of producing superconductor using same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 2002-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120215008-A1 Process for the Preparation of 4-Sulfinyl-Pyrazole Derivatives HCN4, CBR3, SCO2 CA4 36/4885CA2 46/4885CA1 135/4885
US-11814348-B2 Oxidizing liquid media for chemical transformations HAO2, LPO, DUOX1 CA4 300/4885CA2 143/4885CA1 200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.