SCHEMBL1758375

SCHEMBL1758375

O=C1CCCN1CC(O)CO

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.58
PER2 O15055 4/20 0.55
RCE1 Q9Y256 1/20 0.54
TSHR P16473 1/20 0.52
CYP2C19 P33261 2/20 0.51
GAA P10253 1/20 0.51
CRY2 Q49AN0 2/20 0.50
KMT2A Q03164 5/20 0.47
MEN1 O00255 2/20 0.47
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.45
ATM Q13315 1/20 0.45
CYP1A2 P05177 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM5 P08912 1/20 0.41
CYP2D6 P10635 1/20 0.41
CHRM1 P11229 1/20 0.41
CYP2C9 P11712 1/20 0.41
CHRM3 P20309 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31632736 0.93 PER2 (0.55) PIK3CDPER2RCE1TSHRCYP2C19
SCHEMBL9011538 0.90 PIK3CD (0.64) PIK3CDPER2RCE1TSHRCYP2C19
SCHEMBL12020361 0.83 PIK3CD (0.61) PIK3CDPER2RCE1TSHRCYP2C19
SCHEMBL13894757 0.83 PIK3CD (0.56) PIK3CDPER2RCE1TSHRCYP2C19
SCHEMBL1330220 0.83 PIK3CD (0.56) PIK3CDPER2RCE1TSHRCYP2C19
SCHEMBL12501722 0.83 PIK3CD (0.56) PIK3CDPER2RCE1TSHRCYP2C19
SCHEMBL9011512 0.82 PER2 (0.63) PIK3CDPER2RCE1TSHRCYP2C19
SCHEMBL10664050 0.82 PIK3CD (0.64) PIK3CDPER2RCE1TSHRCYP2C19
SCHEMBL23854068 0.81 PIK3CD (0.46) PIK3CDPER2RCE1TSHRCYP2C19
Glycerin SCHEMBL28092430 0.81 PIK3CD (0.46) PIK3CDPER2RCE1TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220315761-A1 DIHYDROXY LACTAM BASED POLYMERS, COMPOSITIONS AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2022-10-06 US claimed
CN-113631632-A Dihydroxylactam-based polymers, compositions thereof and uses thereof ISP投资有限公司 2021-11-09 CN claimed
JP-6292821-A None JP disclosed
US-12552931-B2 Dihydroxy lactam based polymers, compositions and applications thereof ISP INVESTMENTS LLC (US) 2026-02-17 US disclosed
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 US disclosed
US-20220315761-A1 DIHYDROXY LACTAM BASED POLYMERS, COMPOSITIONS AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2022-10-06 US disclosed
EP-3914635-A1 DIHYDROXY LACTAM BASED POLYMERS, COMPOSITIONS AND APPLICATIONS THEREOF ISP Investments LLC (US) 2021-12-01 EP disclosed
CN-113631632-A Dihydroxylactam-based polymers, compositions thereof and uses thereof ISP投资有限公司 2021-11-09 CN disclosed
US-20210332254-A1 Aqueous Ink Jet Compostion And Method For Manufacturing Recorded Matter SEIKO EPSON CORPORATION (JP) 2021-10-28 US disclosed
US-20210301165-A1 Aqueous Ink Jet Composition, Ink Set, Ink Jet Recording Apparatus, And Method For Manufacturing Recorded Matter SEIKO EPSON CORPORATION (JP) 2021-09-30 US disclosed
WO-2020154471-A1 DIHYDROXY LACTAM BASED POLYMERS, COMPOSITIONS AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2020-07-30 WO disclosed
WO-2011056682-A1 REVERSE HEAD GROUP LIPIDS, LIPID PARTICLE COMPOSITIONS COMPRISING REVERSE HEADGROUP LIPIDS, AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2011-05-12 WO disclosed
WO-2011056682-A1 REVERSE HEAD GROUP LIPIDS, LIPID PARTICLE COMPOSITIONS COMPRISING REVERSE HEADGROUP LIPIDS, AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2011-05-12 WO disclosed
WO-1999011690-A1 LOW VISCOSITY POLYURETIDIONE POLYURETHANES AND THEIR USE AS CURATIVES FOR SOLVENT AND WATER BORNE COATINGS ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1999-03-11 WO disclosed
US-5861193-A LIGHTFASTNESS; WEAR, HEAT, SOLVENT, CHEMICAL AND WEATHER RESISTANT; AUTOMOBILE SEAT CUSHIONS ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1999-01-19 US disclosed
US-5814689-A Low viscosity polyuretidione polyurethanes and their use as curatives for solvent and water borne coatings ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1998-09-29 US disclosed
JP-H06292821-A PRODUCTION OF HOLLOW FIBER MEMBRANE TEIJIN LTD 1994-10-21 JP disclosed
US-4842858-A PYRROLIDINYL ALKYLENEOXY POLYMER GAF CORPORATION (US) 1989-06-27 US disclosed
US-4830851-A NONIONIC SURFACTANT, POLYETHER GAF CORPORATION (US) 1989-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552931-B2 Dihydroxy lactam based polymers, compositions and applications thereof PARG, GNE, PGLS PIK3CD 522/4885PER2 3135/4885RCE1 286/4885
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH PIK3CD 1664/4885PER2 2343/4885RCE1 1450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.