Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8255746 | 0.85 | PIK3C2B (0.43) | SLC22A12TSHRLMNAPIK3C2BALDH1A1 | |
| SCHEMBL2542294 | 0.74 | RPS6KA5 (0.41) | SLC22A12PIK3C2BALDH1A1DAOADORA2A | |
| SCHEMBL2539136 | 0.74 | SLC22A12 (0.43) | SLC22A12PIK3C2BDAOADORA2AADORA1 | |
| SCHEMBL8258425 | 0.70 | PIK3C2B (0.43) | TSHRLMNAPIK3C2BALDH1A1KDM4E | |
| SCHEMBL12532489 | 0.69 | LMNA (0.43) | SLC22A12TSHRLMNASLC5A2ALDH1A1 | |
| SCHEMBL8256510 | 0.69 | LMNA (0.43) | LMNASLC5A2ALDH1A1DAO | |
| SCHEMBL8256125 | 0.67 | PIK3C2B (0.46) | TSHRPIK3C2BKDM4EMAPTTDP1 | |
| SCHEMBL14271694 | 0.65 | HSP90AA1 (0.39) | SLC22A12ALDH1A1MAPTDAOADORA2A | |
| SCHEMBL8285519 | 0.65 | TRPC5 (0.54) | LMNAPIK3C2BALDH1A1KDM4EMAPT | |
| SCHEMBL30003476 | 0.63 | TSHR (0.55) | TSHRLMNAALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951704-B1 | 1,3-DIHYDRO-BENZIMIDAZOL-2-YLIDENE AMINES USEFUL FOR THE TREATMENT OR PREVENTION OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-03-16 | — | — | EP | disclosed |