Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2B | O00750 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP9 | P55211 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | KCNJ4 | P48050 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258425 | 0.86 | PIK3C2B (0.43) | PIK3C2BL3MBTL1NPC1RAB9AKDM4E | |
| SCHEMBL17584957 | 0.85 | SLC22A12 (0.39) | PIK3C2BKDM4ETSHRSLC22A12LMNA | |
| SCHEMBL8255748 | 0.83 | PIK3C2B (0.38) | PIK3C2BL3MBTL1NPC1RAB9AKDM4E | |
| SCHEMBL8256125 | 0.82 | PIK3C2B (0.46) | PIK3C2BL3MBTL1KDM4EPIK3CAMTOR | |
| SCHEMBL8285519 | 0.79 | TRPC5 (0.54) | PIK3C2BL3MBTL1NPC1RAB9AKDM4E | |
| SCHEMBL8285520 | 0.79 | TRPC5 (0.46) | PIK3C2BL3MBTL1NPC1RAB9AKDM4E | |
| SCHEMBL8255887 | 0.76 | KCNJ4 (0.37) | L3MBTL1KDM4ETSHRKCNJ4LMNA | |
| SCHEMBL8285540 | 0.71 | TRPC5 (0.46) | PIK3C2BL3MBTL1NPC1RAB9AKDM4E | |
| SCHEMBL2542294 | 0.67 | RPS6KA5 (0.41) | PIK3C2BSLC22A12ALDH1A1POLBKMT2A | |
| SCHEMBL2539136 | 0.67 | SLC22A12 (0.43) | PIK3C2BSLC22A12KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956196-B2 | the major cause of lower respiratory tract illness during infancy and childhood | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2011-06-07 | — | — | US | disclosed |
| US-7956196-B2 | the major cause of lower respiratory tract illness during infancy and childhood | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2011-06-07 | — | — | US | disclosed |
| US-20080146564-A1 | 1,3-Dihydro-Benzimidazol-2-Ylidene Amines as Inhibitors of Respiratory Syncytial Virus Replication | JANSSEN SCIENCES IRELAND UC (IE) | 2008-06-19 | — | — | US | disclosed |
| US-20080146564-A1 | 1,3-Dihydro-Benzimidazol-2-Ylidene Amines as Inhibitors of Respiratory Syncytial Virus Replication | JANSSEN SCIENCES IRELAND UC (IE) | 2008-06-19 | — | — | US | disclosed |
| WO-2006097534-A1 | 1,3-DIHYDRO-BENZIMIDAZOL-2-YLIDENE AMINES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD (IE) | 2006-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146564-A1 | 1,3-Dihydro-Benzimidazol-2-Ylidene Amines as Inhibitors of Respiratory Syncytial Virus Replication | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, RTF2 | PIK3C2B 1353/4885L3MBTL1 1012/4885NPC1 2296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.