Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.41 |
| ▸ | NCS1 | P62166 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | STK16 | O75716 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.39 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.39 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12068382 | 0.83 | NQO2 (0.44) | LRRK2CACNA1DBACE1GAKRIPK2 | |
| SCHEMBL1722692 | 0.80 | KDM4E (0.46) | BACE1NCS1ALDH1A1KDM4E | |
| SCHEMBL12014783 | 0.79 | ALDH1A1 (0.45) | ALDH1A1GFERKDM4ESMN1; SMN2 | |
| SCHEMBL16788276 | 0.77 | KMT2A (0.56) | ALDH1A1GFERKDM4ESMN1; SMN2 | |
| SCHEMBL21642439 | 0.76 | PGK1 (0.38) | LRRK2CACNA1DMBOAT4ALDH1A1GAK | |
| SCHEMBL21090195 | 0.76 | ALDH1A1 (0.43) | BACE1ALDH1A1GFERKDM4ESMN1; SMN2 | |
| SCHEMBL29911314 | 0.76 | ALDH1A1 (0.43) | BACE1ALDH1A1GFERKDM4ESMN1; SMN2 | |
| SCHEMBL1722795 | 0.76 | BACE1 (0.53) | BACE1ALDH1A1GFERKDM4E | |
| SCHEMBL17585456 | 0.76 | ALDH1A1 (0.43) | ALDH1A1GFERGAKKDM4ESMN1; SMN2 | |
| SCHEMBL13347572 | 0.74 | MAPT (0.50) | LRRK2ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685738-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | OCUTERRA THERAPEUTICS, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-20170369490-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FELIQS CORPORATION (JP) | 2017-12-28 | — | — | US | disclosed |
| US-9790222-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-20170291900-A1 | FLUORINATED INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2017-10-12 | — | — | US | disclosed |
| US-9717729-B2 | Fluorinated integrin antagonists | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-08-01 | — | — | US | disclosed |
| US-20170071939-A1 | FLUORINATED INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2017-03-16 | — | — | US | disclosed |
| US-9518053-B2 | Fluorinated integrin antagonists | SCIFLUOR LIFE SCIENCES, INC. (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160244447-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FELIQS CORPORATION (JP) | 2016-08-25 | — | — | US | disclosed |
| US-20160075698-A1 | FLUORINATED INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170071939-A1 | FLUORINATED INTEGRIN ANTAGONISTS | ITGB5, ITGB1, ITGA5 | LRRK2 2732/4885CACNA1D 2041/4885BACE1 4265/4885 |
| US-20170369490-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FFAR3, FFAR2, FFAR1 | LRRK2 2892/4885CACNA1D 3788/4885BACE1 4547/4885 |
| US-11685738-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | FFAR3, FFAR2, FFAR1 | LRRK2 2892/4885CACNA1D 3788/4885BACE1 4547/4885 |
| US-20160244447-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FFAR3, FFAR2, FFAR1 | LRRK2 2892/4885CACNA1D 3788/4885BACE1 4547/4885 |
| US-20160075698-A1 | FLUORINATED INTEGRIN ANTAGONISTS | ITGB5, ITGB1, ITGA5 | LRRK2 2732/4885CACNA1D 2041/4885BACE1 4265/4885 |
| US-20170291900-A1 | FLUORINATED INTEGRIN ANTAGONISTS | ITGB5, ITGB1, ITGA5 | LRRK2 2732/4885CACNA1D 2041/4885BACE1 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.