Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 13/20 | 0.54 |
| ▸ | PDE1A | P54750 | 5/20 | 0.52 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.52 |
| ▸ | PDE1C | Q14123 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758738 | 0.86 | PDE5A (0.48) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1758817 | 0.84 | PDE5A (0.50) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL6880519 | 0.81 | PDE5A (0.52) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1758703 | 0.80 | PDE5A (0.40) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1758692 | 0.79 | PDE5A (0.56) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1758713 | 0.76 | PDE5A (0.54) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1759205 | 0.71 | CNR2 (0.62) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1758918 | 0.70 | PDE5A (0.44) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1758649 | 0.69 | EPHX2 (0.63) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL6880659 | 0.69 | PDE5A (0.47) | PDE5APDE1APDE1BPDE1CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | claimed |
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |