Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16213058 | 0.92 | HDAC1 (0.38) | HDAC1 | |
| SCHEMBL27182150 | 0.83 | GLS (0.30) | — | |
| SCHEMBL16213104 | 0.75 | HDAC1 (0.43) | HDAC1 | |
| SCHEMBL17586136 | 0.74 | SLC7A5 (0.38) | — | |
| SCHEMBL9715241 | 0.69 | F2 (0.38) | — | |
| Hydrochloric Acid SCHEMBL9715397 | 0.68 | F10 (0.42) | — | |
| SCHEMBL16330540 | 0.64 | MIF (0.43) | HDAC1 | |
| SCHEMBL12137652 | 0.64 | P2RX7 (0.38) | — | |
| SCHEMBL3680728 | 0.63 | THRA (0.50) | — | |
| SCHEMBL24276658 | 0.62 | EPHX2 (0.46) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160074541-A1 | Prosthetic Compounds for Labeling Internalizing Biomolecules | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160074541-A1 | Prosthetic Compounds for Labeling Internalizing Biomolecules | CD47, CD2, CD22 | HDAC1 734/4885CYP19A1 4312/4885CNR1 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.