Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879978 | 0.87 | CNR2 (0.45) | CNR2GAAHTTCNR1SMN1; SMN2 | |
| SCHEMBL1758648 | 0.81 | CNR2 (0.60) | CNR2GAAHTTCNR1EPHX2 | |
| SCHEMBL1758686 | 0.75 | HDAC6 (0.34) | CNR2GAAEPHX2NPC1RAB9A | |
| SCHEMBL1759205 | 0.74 | CNR2 (0.62) | CNR2GAAHTTKDM4E | |
| SCHEMBL962008 | 0.73 | CNR2 (0.67) | CNR2GAAHTTCNR1SMN1; SMN2 | |
| SCHEMBL1758714 | 0.70 | CNR2 (0.67) | CNR2GAAHTTCNR1SMN1; SMN2 | |
| SCHEMBL2753853 | 0.70 | ALOX5 (0.64) | CNR2GAAHTTCNR1SMN1; SMN2 | |
| SCHEMBL1548157 | 0.68 | ALOX5 (0.65) | CNR2GAAHTTCNR1SMN1; SMN2 | |
| SCHEMBL1759195 | 0.68 | GAA (0.53) | CNR2GAAHTTKDM4EALDH1A1 | |
| SCHEMBL961304 | 0.66 | EPHX2 (0.66) | CNR2GAAHTTCNR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |