Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 2/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10159905 | 0.86 | AKR1C2 (0.49) | AKR1C2AKR1C1PTGS1PTGS2LMNA | |
| SCHEMBL1355668 | 0.85 | AKR1C2 (0.51) | AKR1C2AKR1C1PTGS1PTGS2LMNA | |
| SCHEMBL28404030 | 0.83 | GABRA1 (0.42) | AKR1C2AKR1C1PTGS1PTGS2LMNA | |
| SCHEMBL4959120 | 0.82 | KLKB1 (0.65) | AKR1C2AKR1C1PTGS1PTGS2LMNA | |
| SCHEMBL6859574 | 0.81 | KLKB1 (0.62) | ESR1TSHRHMGB1CXCL12KLKB1 | |
| SCHEMBL15592319 | 0.81 | AKR1C2 (0.48) | AKR1C2AKR1C1PTGS1PTGS2LMNA | |
| SCHEMBL15936058 | 0.81 | AKR1C2 (0.58) | AKR1C2AKR1C1PTGS1PTGS2LMNA | |
| SCHEMBL11214506 | 0.81 | ALDH1A1 (0.66) | AKR1C2AKR1C1PTGS1PTGS2LMNA | |
| SCHEMBL17586553 | 0.80 | GRIN2D (0.58) | LMNARARBCASRHMGB1CXCL12 | |
| SCHEMBL13652492 | 0.79 | ALDH1A1 (0.50) | AKR1C2AKR1C3RARBHMGB1CXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581554-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2022-04-20 | — | — | EP | disclosed |
| US-10457891-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2019-10-29 | — | — | US | disclosed |
| EP-2994448-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2019-07-31 | — | — | EP | disclosed |
| US-9988592-B2 | Organic compounds | Givaudan, S.A. (CH) | 2018-06-05 | — | — | US | disclosed |
| US-9988592-B2 | Organic compounds | Givaudan, S.A. (CH) | 2018-06-05 | — | — | US | disclosed |
| US-20170218299-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2017-08-03 | — | — | US | disclosed |
| US-20170218299-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2017-08-03 | — | — | US | disclosed |
| US-9656938-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2017-05-23 | — | — | US | disclosed |
| US-9656938-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2017-05-23 | — | — | US | disclosed |
| US-20160075627-A1 | ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075627-A1 | ORGANIC COMPOUNDS | AOX1, TYR, ALK | AKR1C2 374/4885AKR1C1 342/4885PTGS1 1076/4885 |
| US-20170218299-A1 | ORGANIC COMPOUNDS | AOX1, TYR, ALK | AKR1C2 374/4885AKR1C1 342/4885PTGS1 1076/4885 |
| US-10457891-B2 | Organic compounds | AOX1, TYR, ALK | AKR1C2 374/4885AKR1C1 342/4885PTGS1 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.