Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | IL33 | O95760 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTRA2 | O43464 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17589733 | 0.81 | IL33 (0.43) | KMT2AKDM4EPKMNPSR1MAPT | |
| SCHEMBL17589742 | 0.79 | IL33 (0.45) | KMT2AKDM4EPKMNPSR1MAPT | |
| SCHEMBL623099 | 0.71 | IL33 (0.43) | KMT2AKDM4EPKMNPSR1MAPT | |
| SCHEMBL17589738 | 0.70 | IL33 (0.46) | KMT2AKDM4EPKMNPSR1MAPT | |
| SCHEMBL17589732 | 0.70 | IL33 (0.44) | KMT2AKDM4EPKMNPSR1MAPT | |
| SCHEMBL17589740 | 0.70 | IL33 (0.46) | KMT2AKDM4EPKMNPSR1MAPT | |
| SCHEMBL626204 | 0.68 | IL33 (0.46) | KMT2AKDM4EPKMNPSR1MAPT | |
| SCHEMBL18862278 | 0.68 | MAPT (0.59) | KMT2AKDM4EPKMMAPTALDH1A1 | |
| SCHEMBL16316318 | 0.68 | ALDH1A1 (0.49) | KMT2AKDM4EPKMNPSR1MAPT | |
| SCHEMBL623536 | 0.68 | ALDH1A1 (0.52) | KMT2AKDM4EPKMNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255088-B2 | Premature-termination-codons readthrough compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-09 | — | — | US | disclosed |