Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10870487 | 0.88 | CYP3A4 (0.50) | CYP3A4THRBHSD17B10MEN1KMT2A | |
| SCHEMBL6151946 | 0.87 | ELANE (0.46) | HTR2ACYP3A4THRBHSD17B10MEN1 | |
| SCHEMBL159668 | 0.86 | SMN1; SMN2 (0.50) | CYP3A4HTTALDH1A1TSHRTP53 | |
| SCHEMBL9717273 | 0.85 | ALDH1A1 (0.48) | HTR2ACYP3A4THRBHSD17B10ALDH1A1 | |
| SCHEMBL6152948 | 0.83 | CYP3A4 (0.46) | CYP3A4THRBHSD17B10MEN1KMT2A | |
| SCHEMBL28846119 | 0.83 | SRD5A2 (0.42) | CYP3A4THRBHSD17B10HTTALDH1A1 | |
| SCHEMBL166548 | 0.81 | CYP3A4 (0.53) | CYP3A4HSD17B10KMT2AALDH1A1TSHR | |
| SCHEMBL9717275 | 0.81 | KDM4E (0.45) | CYP3A4HSD17B10ALDH1A1TSHRKDM4E | |
| SCHEMBL9174753 | 0.80 | CYP3A4 (0.43) | CYP3A4THRBHSD17B10MEN1KMT2A | |
| SCHEMBL9700576 | 0.80 | CYP3A4 (0.43) | CYP3A4THRBHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611504-A1 | CARBONATE DERIVATIVES AS SKIN CARE | Eastman Chemical Company (US) | 2013-07-10 | — | — | EP | claimed |
| US-20120059056-A1 | CARBONATE DERIVATIVES AS SKIN CARE | EASTMAN CHEMICAL COMPANY (US) | 2012-03-08 | — | — | US | claimed |
| WO-2012030603-A1 | CARBONATE DERIVATIVES AS SKIN CARE | EASTMAN CHEMICAL COMPANY (US) | 2012-03-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059056-A1 | CARBONATE DERIVATIVES AS SKIN CARE | GLA, TYR, GANC | HTR2A 4577/4885CYP3A4 1585/4885THRB 4622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.