Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680444 | 0.90 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL29195593 | 0.89 | LMNA (0.50) | SMN1; SMN2ALDH1A1CYP3A4HTTNPC1 | |
| SCHEMBL292834 | 0.87 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1HTTNPC1POLB | |
| SCHEMBL175910 | 0.86 | HTR2A (0.49) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL4679934 | 0.86 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL4680610 | 0.85 | CYP3A4 (0.48) | ALDH1A1CYP3A4TSHRHTTMMP9 | |
| SCHEMBL174408 | 0.81 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1TP53CYP3A4HTT | |
| SCHEMBL697620 | 0.80 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1HTTNPC1POLB | |
| SCHEMBL22028109 | 0.80 | LTA4H (0.58) | SMN1; SMN2ALDH1A1HTTNPC1POLB | |
| SCHEMBL166548 | 0.80 | CYP3A4 (0.53) | SMN1; SMN2ALDH1A1CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1744 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991655-B1 | COMPOSITIONS AND METHODS FOR ALTERING SECOND MESSENGER SIGNALING | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2024-04-10 | — | — | EP | claimed |
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | claimed |
| EP-3092220-B1 | VITAMIN C PRODRUGS AND USES THEREOF | UNIV FLORIDA (US) | 2021-01-20 | — | — | EP | claimed |
| US-10870651-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-12-22 | — | — | US | claimed |
| EP-2016044-B1 | PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | HARVARD COLLEGE (US) | 2020-06-10 | — | — | EP | claimed |
| EP-3063164-B1 | SYNTHETIC ROUTE TO 2'-DEOXY-2',2'-DIFLUOROTETRAHYDROURIDINES | OTSUKA PHARMA CO LTD (JP) | 2018-12-05 | — | — | EP | claimed |
| US-9856225-B2 | Substituted phenazines as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-01-02 | — | — | US | claimed |
| EP-2550285-B1 | TRIOXACARCINS AND USES THEREOF | HARVARD COLLEGE (US) | 2017-07-19 | — | — | EP | claimed |
| US-20150376201-A1 | CORTISTATIN ANALOGUES AND SYNTHESES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-12-31 | — | — | US | claimed |
| US-12037355-B2 | Triterpene saponin analogues | ADJUVANCE TECHNOLOGIES, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| CN-118355117-A | Oligonucleotide compositions and methods thereof | 波涛生命科学有限公司 | 2024-07-16 | — | — | CN | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| US-20240229026-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES LTD. (SG) | 2024-07-11 | — | — | US | disclosed |
| EP-4398254-A2 | COMPOSITIONS AND METHODS FOR ALTERING SECOND MESSENGER SIGNALING | Memorial Sloan Kettering Cancer Center (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2007008226-A9 | PALLADIUM-CATALYZED CARBON-CARBON BOND FORMING REACTIONS | HARVARD COLLEGE (US) | 2007-05-24 | — | — | WO | disclosed |
| US-20070066851-A1 | Palladium-catalyzed carbon-carbon bond forming reactions | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2007-03-22 | — | — | US | disclosed |
| WO-2007008226-A2 | PALLADIUM-CATALYZED CARBON-CARBON BOND FORMING REACTIONS | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-01-18 | — | — | WO | disclosed |
| WO-2006138380-A2 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060287520-A1 | Synthesis of salinosporamide A and analogues thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-12-21 | — | — | US | disclosed |
| US-20050282787-A1 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066851-A1 | Palladium-catalyzed carbon-carbon bond forming reactions | APEX1, PCNA, DNMT3A | SMN1; SMN2 3654/4885ALDH1A1 564/4885TP53 2229/4885 |
| US-20050282787-A1 | Synthesis of tetracyclines and analogues thereof | TET1, TET3, MYC | SMN1; SMN2 3539/4885ALDH1A1 4455/4885TP53 2188/4885 |
| US-20240229026-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | SMN1; SMN2 695/4885ALDH1A1 2867/4885TP53 1404/4885 |
| US-20150376201-A1 | CORTISTATIN ANALOGUES AND SYNTHESES THEREOF | CTTN, TEK, FLT1 | SMN1; SMN2 4322/4885ALDH1A1 2344/4885TP53 1624/4885 |
| US-10870651-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | CDK7, CDK3, CDK9 | SMN1; SMN2 1868/4885ALDH1A1 4404/4885TP53 164/4885 |
| US-12037355-B2 | Triterpene saponin analogues | LSS, NFATC1, PGGT1B | SMN1; SMN2 4162/4885ALDH1A1 4821/4885TP53 1236/4885 |
| US-20060287520-A1 | Synthesis of salinosporamide A and analogues thereof | PSMB5, ERG28, PSMB11 | SMN1; SMN2 2614/4885ALDH1A1 2428/4885TP53 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.