Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 8/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226049 | 0.86 | FEN1 (0.44) | FEN1RXRARXRBRXRGBCHE | |
| SCHEMBL19905553 | 0.81 | PTGER4 (0.56) | RXRARXRBRXRGBCHEPTGER4 | |
| SCHEMBL1759295 | 0.81 | FEN1 (0.42) | FEN1RXRARXRBRXRGPTGER4 | |
| SCHEMBL1638152 | 0.80 | RXRA (0.45) | FEN1RXRARXRBRXRGBCHE | |
| SCHEMBL16809426 | 0.78 | HTR1A (0.48) | RXRARXRBBCHEPTGER4PTGER3 | |
| SCHEMBL1758960 | 0.77 | PTGER4 (0.44) | RXRARXRBRXRGBCHEPTGER4 | |
| SCHEMBL4770022 | 0.77 | ALOX5AP (0.46) | RXRARXRBRXRGPTGER4PTGER3 | |
| SCHEMBL5810886 | 0.76 | NPC1 (0.41) | BCHEMAOAMAOBL3MBTL1KDM4E | |
| SCHEMBL7033667 | 0.75 | ALDH1A1 (0.40) | RXRARXRBRXRGBCHEKDM4E | |
| SCHEMBL1637804 | 0.75 | TDP1 (0.48) | FEN1RXRARXRBRXRGPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493932-A2 | CATALYST COMPOUNDS AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056423-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |