Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 7/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.98 |
| ▸ | MAPT | P10636 | 5/20 | 0.98 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.98 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.98 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.98 |
| ▸ | BLM | P54132 | 3/20 | 0.98 |
| ▸ | LMNA | P02545 | 3/20 | 0.98 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.98 |
| ▸ | MEN1 | O00255 | 2/20 | 0.98 |
| ▸ | GMNN | O75496 | 2/20 | 0.98 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.98 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.98 |
| ▸ | MTOR | P42345 | 2/20 | 0.98 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.98 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenretinide SCHEMBL17593528 | 1.00 | RBP4 (0.98) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL11703 | 0.99 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL19121 | 0.99 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL15703189 | 0.99 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL10629371 | 0.99 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL4874840 | 0.99 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL13402304 | 0.99 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL11704 | 0.99 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL839699 | 0.99 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL9838209 | 0.99 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016038534-A1 | FENRETINIDE COMPLEXES | ISTITUTI FISIOTERAPICI OSPITALIERI (IFO) - ISTITUTO REGINA ELENA PER LO STUDIO E LA CURA DEI TUMORI (IT) | 2016-03-17 | — | — | WO | disclosed |