Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | BLM | P54132 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | GMNN | O75496 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | MTOR | P42345 | 2/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenretinide SCHEMBL4996036 | 1.00 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL13402304 | 1.00 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL9838209 | 1.00 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL19121 | 1.00 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL15703189 | 1.00 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL11704 | 1.00 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL10629371 | 1.00 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL11703 | 1.00 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL4874840 | 1.00 | RBP4 (1.00) | RBP4ALDH1A1MAPTHIF1ACYP3A4 | |
| Fenretinide SCHEMBL17593790 | 0.99 | RBP4 (0.98) | RBP4ALDH1A1MAPTHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567702-A | TREATING ALOPECIA | L'OREAL (FR) | 1996-10-22 | — | — | US | claimed |
| US-5192534-A | Composition for inducing and stimulating hair growth and/or retarding its loss, based on pyrimidine derivatives and sunscreens | L'OREAL (FR) | 1993-03-09 | — | — | US | claimed |
| EP-0376821-B1 | COMPOSITIONS FOR INDUCING AND STIMULATING HAIR GROWTH AND/OR STOP THEIR FALL BASED ON PYRIMIDINE DERIVATIVES AND UV FILTERS | L'OREAL (FR) | 1992-08-26 | — | — | EP | claimed |
| US-4323581-A | N-(4-HYDROXYPHENYL)-ALL-TRANS-RETINAMIDE | JOHNSON & JOHNSON (US) | 1982-04-06 | — | — | US | claimed |
| US-4190594-A | ABSORBERS OF ULTRAVIOLET RADIATION | JOHNSON & JOHNSON (US) | 1980-02-26 | — | — | US | claimed |
| US-20190117590-A1 | Compositions and Methods for Treating Hyperproliferative Disorders | TEXAS TECH UNIVERSITY SYSTEM | 2019-04-25 | — | — | US | disclosed |
| EP-2669267-B1 | Compositions and methods for treating hyperproliferative disorders | TEXAS TECH UNIV (US) | 2018-01-10 | — | — | EP | disclosed |
| EP-1594544-B1 | ORAL COMPOSITIONS OF FENRETINIDE HAVING INCREASED BIOAVAILABILITY AND METHODS OF USING THE SAME | LOS ANGELES CHILDRENS HOSPITAL (US) | 2016-04-06 | — | — | EP | disclosed |
| EP-1722771-B1 | COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING AN INFLAMMATORY RESPONSE | UNIV MCGILL (CA) | 2014-04-23 | — | — | EP | disclosed |
| US-8642658-B2 | Treatment of neural diseases or conditions | ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2014-02-04 | — | — | US | disclosed |
| EP-2669267-A1 | Compositions and methods for treating hyperproliferative disorders | TEXAS TECH UNIVERSITY (US) | 2013-12-04 | — | — | EP | disclosed |
| US-20130217691-A1 | Compositions and Methods for Treating Hyperproliferative Disorders | TEXAS TECH UNIVERSITY SYSTEM (US) | 2013-08-22 | — | — | US | disclosed |
| US-4190594-A | ABSORBERS OF ULTRAVIOLET RADIATION | JOHNSON & JOHNSON (US) | 1980-02-26 | — | — | US | disclosed |
| US-4129662-A | Retinoic acid derivatives for the treatment of acne | JOHNSON & JOHNSON (US) | 1978-12-12 | — | — | US | disclosed |
| US-4126693-A | RETINOIC ACID DERIVATIVES IN THE TREATMENT OF ACNE | JOHNSON & JOHNSON (US) | 1978-11-21 | — | — | US | disclosed |
| US-4126699-A | RETINOIC ACID DERIVATIVES FOR THE TREATMENT OF ACNE | JOHNSON & JOHNSON (US) | 1978-11-21 | — | — | US | disclosed |
| US-4126698-A | RETINOIC ACID DERIVATIVES IN THE TREATMENT OF ACNE | JOHNSON & JOHNSON (US) | 1978-11-21 | — | — | US | disclosed |
| US-4126697-A | RETINOIC ACID DERIVATIVES IN THE TREATMENT OF ACNE | JOHNSON & JOHNSON (US) | 1978-11-21 | — | — | US | disclosed |
| US-4108880-A | ULTRAVIOLET ABSORBERS | JOHNSON & JOHNSON (US) | 1978-08-22 | — | — | US | disclosed |
| US-4055659-A | Retinoic acid derivatives | JOHNSON & JOHNSON (US) | 1977-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190117590-A1 | Compositions and Methods for Treating Hyperproliferative Disorders | SGMS1, S1PR1, SPHK1 | RBP4 385/4885ALDH1A1 1300/4885MAPT 2661/4885 |
| US-20130217691-A1 | Compositions and Methods for Treating Hyperproliferative Disorders | SGMS1, S1PR1, SPHK1 | RBP4 385/4885ALDH1A1 1300/4885MAPT 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.