SCHEMBL1759386

SCHEMBL1759386

COC(=O)Cc1ccccc1C(Cl)(Cl)Cl

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
TSHR P16473 1/20 0.41
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
SMN1; SMN2 Q16637 5/20 0.38
NPC1 O15118 2/20 0.38
TP53 P04637 2/20 0.38
RAB9A P51151 2/20 0.38
POLB P06746 2/20 0.38
HPGD P15428 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.38
HSD17B10 Q99714 1/20 0.38
POLQ O75417 1/20 0.38
LMNA P02545 1/20 0.37
ACLY P53396 1/20 0.37
CFD P00746 1/20 0.37
EGFR P00533 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14803742 0.84 KDM4E (0.44) KDM4ETSHRCYP4F2CYP4A11SMN1; SMN2
SCHEMBL871601 0.83 POLQ (0.55) KDM4EPOLBALDH1A1POLQ
SCHEMBL30474543 0.83 POLQ (0.55) KDM4EPOLBALDH1A1POLQ
SCHEMBL1554320 0.81 KDM4E (0.53) KDM4ETSHRCYP4F2CYP4A11SMN1; SMN2
SCHEMBL872658 0.80 NPC1 (0.52) KDM4ESMN1; SMN2NPC1TP53RAB9A
SCHEMBL29498164 0.80 NPC1 (0.52) KDM4ESMN1; SMN2NPC1TP53RAB9A
SCHEMBL12048690 0.79 KDM4E (0.41) KDM4ETSHRCYP4F2CYP4A11SMN1; SMN2
Hydrochloric Acid SCHEMBL27455925 0.79 NPC1 (0.50) KDM4ESMN1; SMN2NPC1TP53RAB9A
SCHEMBL4309048 0.78 KDM4E (0.48) KDM4ETSHRCYP4F2CYP4A11SMN1; SMN2
SCHEMBL13948346 0.77 KDM4E (0.47) KDM4ETSHRCYP4F2CYP4A11SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
WO-2025075611-A1 ULTRASONIC INDICATOR BASED ON EMULSION FORMATION JP LABORATORIES, INC. (US) 2025-04-10 WO claimed
EP-3490389-B1 FRAGRANCE AND FLAVOR COMPOSITIONS CONTAINING ISOMERIC ALKADIENYL ESTERS BEDOUKIAN RES INC (US) 2024-09-25 EP claimed
US-20240057595-A1 INSECT REPELLENT COMPOSITIONS SYMBIOTIC CAPITAL AGENCY LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT 2024-02-22 US claimed
WO-2022147076-A1 INSECT REPELLENT COMPOSITIONS MANUS BIO INC. (US) 2022-07-07 WO claimed
US-10863758-B2 Fragrance and flavor compositions containing isomeric alkadienyl esters BEDOUKIAN RESEARCH, INC. (US) 2020-12-15 US claimed
EP-3183231-B1 PERFUME COMPOSITIONS CONTAINING ISOMERIC ALKADIENENITRILES BEDOUKIAN RES INC (US) 2019-10-09 EP claimed
EP-3183330-B1 PERFUME COMPOSITIONS CONTAINING ISOMERIC ALKADIENALS BEDOUKIAN RES INC (US) 2019-07-17 EP claimed
EP-3490389-A1 FRAGRANCE AND FLAVOR COMPOSITIONS CONTAINING ISOMERIC ALKADIENYL ESTERS Bedoukian Research, Inc. (US) 2019-06-05 EP claimed
EP-3386319-A1 FRAGRANCE AND FLAVOR COMPOSITIONS CONTAINING ISOMERIC ALKADIENALS OR ISOMERIC ALKADIENENITRILES Bedoukian Research, Inc. (US) 2018-10-17 EP claimed
US-20160052872-A1 PERFUME COMPOSITIONS CONTAINING ISOMERIC ALKADIENENITRILES BEDOUKIAN RESEARCH, INC. 2016-02-25 US claimed
WO-2016028897-A1 PERFUME COMPOSITONS CONTAINING ISOMERIC ALKADIENENITRILES BEDOUKIAN RESEARCH, INC. (US) 2016-02-25 WO claimed
WO-2016028892-A1 PERFUME COMPOSITIONS CONTAINING ISOMERIC ALKADIENALS BEDOUKIAN RESEARCH, INC. (US) 2016-02-25 WO claimed
WO-2011060028-A1 LIQUID LAUNDRY DETERGENT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2011-05-19 WO claimed
WO-2011059714-A1 SOLID LAUNDRY DETERGENT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2011-05-19 WO claimed
EP-2322595-A1 Solid laundry detergent composition The Procter & Gamble Company (US) 2011-05-18 EP claimed
EP-2322593-A1 Liquid laundry detergent composition The Procter & Gamble Company (US) 2011-05-18 EP claimed
US-20110112005-A1 Laundry Detergent Composition PROCTER & GAMBLE COMPANY, THE 2011-05-12 US claimed
US-7648953-B2 Eco-friendly laundry detergent compositions comprising natural essence THE DIAL CORPORATION (US) 2010-01-19 US claimed
US-20090281010-A1 Eco-friendly laundry detergent compositions comprising natural essence HENKEL AG & CO. KGAA (DE) 2009-11-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160052872-A1 PERFUME COMPOSITIONS CONTAINING ISOMERIC ALKADIENENITRILES OR10J3, ACSL4, CASP4 KDM4E 819/4885TSHR 4859/4885CYP4F2 996/4885
US-10863758-B2 Fragrance and flavor compositions containing isomeric alkadienyl esters FADS2, FADS1, DHCR24 KDM4E 2907/4885TSHR 3126/4885CYP4F2 1063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.