Leucine

Leucine

SCHEMBL175941

CC(C)C[C@H](N)C(=O)O.CC(C)C[C@H](N)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 1.00
SLC1A2 P43004 7/20 0.74
SLC1A3 P43003 6/20 0.74
SLC1A1 P43005 7/20 0.62
GRIK1 P39086 9/20 0.52
GRIK2 Q13002 6/20 0.52
RNPEP Q9H4A4 1/20 0.50
GRIA2 P42262 2/20 0.48
GRIA4 P48058 2/20 0.48
GRIK3 Q13003 2/20 0.48
GRIK5 Q16478 2/20 0.48
GRIA1 P42261 1/20 0.48
PTGS1 P23219 1/20 0.48
SLC7A11 Q9UPY5 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Leucine SCHEMBL175940 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL8568063 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
D-Leucine SCHEMBL9449950 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL20362356 1.00
Leucine SCHEMBL3888 1.00
D-Leucine SCHEMBL42012 1.00
Leucine SCHEMBL25241602 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL8568060 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL331557 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1
Leucine SCHEMBL2478164 1.00 SLC7A5 (1.00) SLC7A5SLC1A2SLC1A3SLC1A1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120129690-A Dual receptor targeted radioligands and uses thereof 辐联科技香港有限公司 2025-06-10 CN claimed
US-10471034-B2 Amino acid compositions and methods for the treatment of liver diseases AXCELLA HEALTH INC. (US) 2019-11-12 US claimed
EP-4746895-A1 A PEPTIDE COMPOSITION AND USES THEREOF OPTM.RX Ltd (IL) 2026-05-27 EP disclosed
CN-120129690-A Dual receptor targeted radioligands and uses thereof 辐联科技香港有限公司 2025-06-10 CN disclosed
CN-119413754-A Amino acid chiral identification method based on artificial intelligence 北京邮电大学 2025-02-11 CN disclosed
WO-2025017561-A1 A PEPTIDE COMPOSITION AND USES THEREOF OPTM.RX LTD (IL) 2025-01-23 WO disclosed
CN-111278848-B TALE RVD for specifically recognizing methylation modified DNA base and application thereof 北京大学 2023-06-27 CN disclosed
CN-114008452-A Method for evaluating food related to cognitive function 味之素株式会社 2022-02-01 CN disclosed
CN-113308122-A Degradable protein plastic and preparation method thereof 清华大学 2021-08-27 CN disclosed
CN-106834229-B Serum-free culture medium for in vitro amplification of human immune killer cells 华东理工大学 2021-08-17 CN disclosed
CN-113180248-A Composition with effects of dispelling effects of alcohol and protecting liver and preparation method and health-care product thereof 海南蛛王生物科技有限公司 2021-07-30 CN disclosed
US-5510244-A TREATING SAMPLES WITH L-DEHYDROGENASE AND/OR D-HYDROGENASE AND A COENZYME, THEN MEASUREMENT OF PRODUCT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1996-04-23 US disclosed
EP-0504168-A4 SYNTHETIC CALCITONIN PEPTIDES 1993-09-22 EP disclosed
EP-0504168-A1 SYNTHETIC CALCITONIN PEPTIDES VICAL, INC. (US) 1992-09-23 EP disclosed
US-5134073-A Culture product of zoogloea ramigera DEGUSSA AKTIENGESELLSCHAFT (DE) 1992-07-28 US disclosed
US-5100916-A Inhibits acetaldehyde dehydrogenase BIO-TOX DIAGNOSTICS KOMMANDITBOLAG (SE) 1992-03-31 US disclosed
WO-1991007978-A1 SYNTHETIC CALCITONIN PEPTIDES VICAL, INC. (US) 1991-06-13 WO disclosed
EP-0417113-A1 Preparation of carbamic acid ester for the treatment of addiction to alcohol BIOTOX DIAGNOSTICS KOMMANDITBOLAG (SE) 1991-03-20 EP disclosed
WO-1989009208-A1 CARBAMIC ACID ESTER AND A PREPARATION THEREOF FOR TREATMENT OF ADDICTION TO ALCOHOL BIO-TOX DIAGNOSTICS KOMMANDITBOLAG (SE) 1989-10-05 WO disclosed
US-4871716-A CROSSLINKED PROTEIN OR POLYPEPTIDE UNIVERSITY OF FLORIDA (US) 1989-10-03 US disclosed