Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759845 | 0.77 | TXNRD1 (0.55) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL29475755 | 0.76 | KDM4E (0.44) | MAPTKMT2AMEN1POLBATM | |
| SCHEMBL4763968 | 0.76 | KDM4E (0.44) | MAPTKMT2AMEN1POLBATM | |
| SCHEMBL3107098 | 0.74 | ATM (0.55) | MAPTKMT2AMEN1LMNAP2RX4 | |
| SCHEMBL29525910 | 0.74 | ATM (0.55) | MAPTKMT2AMEN1LMNAP2RX4 | |
| SCHEMBL24284768 | 0.73 | ALDH1A1 (0.40) | MAPTKMT2AMEN1LMNAP2RX4 | |
| SCHEMBL27936304 | 0.71 | MAPT (0.82) | MAPTKMT2AMEN1LMNAP2RX4 | |
| SCHEMBL30002356 | 0.69 | P2RX4 (0.47) | MAPTP2RX4ATMALDH1A1GAA | |
| SCHEMBL29475756 | 0.69 | HPGD (0.49) | MAPTKMT2AMEN1LMNAP2RX4 | |
| SCHEMBL16694429 | 0.69 | HPGD (0.49) | MAPTKMT2AMEN1LMNAP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060113-A1 | SULFENAMIDE COMPOUNDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011060113-A1 | SULFENAMIDE COMPOUNDS FOR PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2011-05-19 | — | — | WO | disclosed |